https://www.ncbi.nlm.nih.gov/pubmed/30043430 Liver transplant

Pediatr Transplant. 2018 Jul 24:e13251. doi: 10.1111/petr.13251. [Epub ahead of print].Rebound thymic hyperplasia after liver transplantation for a child with biliary atresia; a case report.Wang TK1, Kuo FY2, Lee SY3, Cheng YF4, Elsarawy AM1, Lin CC1, Lin TL1, Chen CL1.

Abstract

The thymus gland possesses the ability to regrow in children leading to a newly developed anterior mediastinal mass. This condition may represent a rebound phenomenon during recovery from a stressful event such as post-chemotherapy and hence was described as RTH. RTH after LT has not been well documented. We are reporting an infant with BA who underwent LT and presented with a symptomless anterior mediastinal mass, detected on follow-up imaging 6 months thereafter. Surgical partial excision was performed to rule out other differential diagnoses of a solid mass in the anterior mediastinum of an infant particularly lymphoma-that may arise as post-transplant lymphoproliferative disorder-and teratoma, as well as the other aggressive lesions such as thymoma and thymic carcinoma. The final pathological analysis revealed true thymic hyperplasia, consistent with RTH. The diagnosis of RTH should be considered for a childpresenting by anterior mediastinal mass after LT.

Published on: 
Jul-2018

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