http://www.ncbi.nlm.nih.gov/pubmed/24345835

Wen JW, Haber BA. Maternal-fetal transmission of hepatitis C infection: what is so special about babies? J PediatrGastroenterolNutr. 2014; 58(3): 278-82.

Children with hepatitis C virus infection often differ from adults regarding the rate of viral clearance, duration of infection, and the progression to cirrhosis. In the pediatric population, vertical transmission of hepatitis C virus infection from mother to infant is the most common route of infection. In the present review, we explore the factors that may influence the natural history of hepatitis C virus infection in children who acquire the infection through maternal-fetal transmission. There is particular focus on how viral diversity and the infant immune system may affect viral transmission. An enhanced understanding of maternal-fetal transmission of hepatitis C virus infection has the potential to affect effective drug and vaccine development for both children and adults.

Published on: 
Mar-2014

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