Event Videos

https://pubmed.ncbi.nlm.nih.gov/37867246/ acute liver failure

Transplantation. 2023 Oct 23.
doi: 10.1097/TP.0000000000004845. Online ahead of print.

CHALF Score: A Novel Tool to Rapidly Risk Stratify Children in Need of Liver Transplant Evaluation During Acute Liver Failure

Johanna M Ascher-Bartlett 1 2, Sarah Bangerth 2 3, Shannon Jordan 2 3, Carly Weaver 1, Sarah Barhouma 2 3, Kambiz Etesami 2 3, Rohit Kohli 1 2, Juliet Emamaullee 2 3

Abstract

Background: Pediatric acute liver failure (PALF) can require emergent liver transplantation (LT, >25%) or lead to death (~15%). Existing models cannot predict clinical trajectory or survival with native liver (SNL). We aimed to create a predictive model for PALF clinical outcomes based on admission variables.

Published on: 
Oct-2023

https://pubmed.ncbi.nlm.nih.gov/37907911/ biliary atresia

Observational Study

BMC Pediatr. 2023 Oct 31;23(1):549.
doi: 10.1186/s12887-023-04370-x.

Development and validation of a model for early diagnosis of biliary atresia

Zongrong Gong 1 2, Lin Lin 2, Gen Lu 2, Chaomin Wan 3 4

Abstract

Background and aims: Early diagnosis of biliary atresia (BA), particularly distinguishing it from other causes of neonatal cholestasis (NC), is challenging. This study aimed to design and validate a predictive model for BA by using the data available at the initial presentation.

Published on: 
Oct-2023

https://pubmed.ncbi.nlm.nih.gov/37870272/ NAFLD

Hepatology. 2023 Oct 23.
doi: 10.1097/HEP.0000000000000644. Online ahead of print.

Development of Fibro-PeN, a clinical prediction model for moderate to severe fibrosis in children with nonalcoholic fatty liver disease

Andrew Wang 1 2, Amanda L Blackford 3, Cynthia Behling 1, Laura A Wilson 4, Kimberly P Newton 1 2, Stavra A Xanthakos 5, Mark H Fishbein 6, Miriam B Vos 7, Marialena Mouzaki 8, Jean P Molleston 9, Ajay K Jain 10, Paula Hertel 11, Kathryn Harlow Adams 9, Jeffrey B Schwimmer 1 2; NASH CRN

Published on: 
Oct-2023

https://pubmed.ncbi.nlm.nih.gov/37587287/ HEPATOLOGY

Hepatol Int. 2023 Aug 16.
doi: 10.1007/s12072-023-10571-4. Online ahead of print.

Live donor liver transplantation for pediatric acute liver failure: challenges and outcomes

Viniyendra Pamecha 1, Nilesh Sadashiv Patil 2, Sanyam Falari 2, Nihar Mohapatra 2, Anubhav Harshit Kumar 2, Gaurav Sindwani 3, Neha Garg 3, Seema Alam 4, Rajeev Khanna 4, Vikrant Sood 4, Bikrant Bihari Lal 4

Abstract
Objective: This study aimed at studying the challenges and outcomes of live-donor liver transplantation (LDLT) for pediatric acute liver failure (PALF).

Published on: 
Aug-2023

https://pubmed.ncbi.nlm.nih.gov/37886236/ neonatal cholestasis

Front Pediatr. 2023 Oct 11:11:1275162.
doi: 10.3389/fped.2023.1275162. eCollection 2023.

Neonatal cholestasis as the onset symptom of McCune-Albright syndrome: case reports and a literature review

Weiyuan Fang # 1, Yanhui Zhang # 2, Lian Chen 3, Xinbao Xie 1

Abstract

Aim: This study aimed to summarize and show the characteristics and evolutionary process of neonatal cholestasis caused by McCune-Albright syndrome (MAS), as neonatal cholestasis may be the initial manifestation of MAS before other classic clinical features appear.

Published on: 
Oct-2023

https://pubmed.ncbi.nlm.nih.gov/37893503/ NAFLD

Randomized Controlled Trial

Medicina (Kaunas). 2023 Oct 7;59(10):1785.
doi: 10.3390/medicina59101785.

Metabolomic Phenotype of Hepatic Steatosis and Fibrosis in Mexican Children Living with Obesity

Nayely Garibay-Nieto 1, Karen Pedraza-Escudero 1, Isabel Omaña-Guzmán 1, María José Garcés-Hernández 1, Eréndira Villanueva-Ortega 1, Mariana Flores-Torres 2, José Luis Pérez-Hernández 3, Mireya León-Hernández 4, Estibalitz Laresgoiti-Servitje 5, Berenice Palacios-González 6, Juan Carlos López-Alvarenga 7, Mauricio Lisker-Melman 8, Felipe Vadillo-Ortega 2

Abstract

Published on: 
Oct-2023

https://pubmed.ncbi.nlm.nih.gov/37600617/ LIVER TRANSPLANT

JPGN Rep. 2023 Jun 9;4(3):e318.
doi: 10.1097/PG9.0000000000000318. eCollection 2023 Aug.

Poor Access to Liver Transplantation and Survival of Children With Acute Liver Failure, Acute-on-chronic Liver Failure or Chronic Liver Disease

Emma Valeria Estrada-Arce 1 2, Renata Aguila-Cano 1 2, Juan Carlos Lona-Reyes 3 4, Laura Esther Flores-Fong 1 2, Elva Rivera-Chávez 1

Abstract

Published on: 
Aug-2023

https://pubmed.ncbi.nlm.nih.gov/37902507/ cholestatic liver disease

Hepatol Commun. 2023 Oct 31;7(11):e0293.
doi: 10.1097/HC9.0000000000000293.eCollection 2023 Nov 1.

Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease

Julia M Boster 1, Nathan P Goodrich 2, Cathie Spino 3, Kathleen M Loomes 4, Estella M Alonso 5, Binita M Kamath 6, Ronald J Sokol 1, Saul Karpen 7, Alexander Miethke 8, Benjamin L Shneider 9, Jean P Molleston 10, Rohit Kohli 11, Simon P Horslen 12, Philip Rosenthal 13, Pamela L Valentino 14, Jeffrey H Teckman 15, Thomas N Hangartner 16, Shikha S Sundaram 1; Childhood Liver Disease Research Network (ChiLDReN)

Abstract

Published on: 
Oct-2023

https://pubmed.ncbi.nlm.nih.gov/37600623/ CHRONIC LIVER DISEASE

JPGN Rep. 2023 Jun 9;4(3):e324.
doi: 10.1097/PG9.0000000000000324. eCollection 2023 Aug.

Hypocoagulability in Children With Decompensated Chronic Liver Disease and Sepsis: Assessment by Thromboelastography

Vignesh Vinayagamoorthy 1, Anshu Srivastava 1, Indranil Das 2, Anupam Verma 2, Prabhakar Mishra 3, Moinak Sen Sarma 1, Ujjal Poddar 1, Surender Kumar Yachha 1

Abstract

Objective: To evaluate the coagulation status of children with decompensated chronic liver disease (DCLD) and infection and factors affecting it using thromboelastography (TEG).

Published on: 
Aug-2023

CLF Intro movie

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