https://www.ncbi.nlm.nih.gov/pubmed/28612320

Shailja Vajpayee, R K Gupta, M L Gupta

Abstract

Neonatal hepatitis with acute liver failure due to varied etiology including various infections is reported in the past. Scrub typhus as a cause of neonatal hepatitis has rarely been reported in literature. A high index of clinical suspicion is required for early diagnosis and timely treatment. Severity and prognosis of the disease varies widely because several different strains of Orientia tsutsugamushi exist with different virulence. Delayed diagnosis can result in complication and significant morbidity and mortality. Here, we report three cases of neonatal hepatitis with acute liver failure caused by scrub typhus to increase awareness.

KEYWORDS:
Eschar; Hepatitis; Neonatal acute liver failure; Neonatal scrub typhus