https://www.ncbi.nlm.nih.gov/pubmed/32108011

Infect Disord Drug Targets. 2020 Feb 27. doi: 10.2174/1871526520666200228104316. [Epub ahead of print]

Cystic echinococcosis in children: high frequency of multiple organ involvement in North of Iran.

Mohammadi M1, Mamishi S2, Pourakbari B2, Faraz Z1, Khodabandeh M3, Mahmoudi S2.

Abstract

INTRODUCTION:
Echinococcosis as an important zoonotic infection has a major worldwide distribution. Pediatric echinococcosis has still become a health concerning issue in developing countries specifically in the Middle East and Iran. The aim of this study was to investigate the human echinococcosis in children in the northern Iran.

MATERIAL AND METHODS:
Patients admitted to the pediatric subspecialty hospital of Amir Kala, Babol, Iran from 2011 to 2016 with a confirmed diagnosis of echinococcosis were reviewed. Records of the patients including demographic data, clinical manifestations of the disease, type of cysts and other related factors were collected.

RESULTS:
Sixteen pediatric patients, twelve (75%) male and four (25%) female were evaluated. All cases had cystic echinococcosis. The results showed that fever (75%) following vomiting, nausea, and coughing (44%) were the most common clinical manifestations. The most common localizations of cases were determined as liver (n=10, 62.5%) and lung (n=9, 56%). The frequency of involvement of more than one organ was 31% (5 cases). The co-occurrence of liverand lung was seen in 2 (12.5%) cases and in one case co-occurrence of liver and spleen was reported. In one case lung, liver and, the pelvis was involved, while in another case liver, sub diaphragm and kidney involvement were observed.

CONCLUSION:
Cystic echinococcosis should be kept in mind when a cystic lesion is encountered anywhere in the body, particularly in patients lining in the endemic regions. Since cystic echinococcosis has a considerable economic impact in Iran, the implementation of a control program as well as the surveillance system are highly recommended to reduce the economic burden of this disease.