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https://pubmed.ncbi.nlm.nih.gov/35258491/ Autoimmune liver disease

J Pediatr Gastroenterol Nutr. 2022 Mar 8.
doi: 10.1097/MPG.0000000000003443.Online ahead of print.

Expression of IL-37 Correlates with Immune Cell Infiltrate and Fibrosis in Pediatric Autoimmune Liver Diseases

Lucas Griessmair 1 2, Laura Pirringer 1, Steffeni Mountford 1, Andrea Sendelhofert 3, Marie-Christine Makeschin 3, Sibylle Koletzko 1, Doris Mayr 3, Philip Bufler 2
Abstract

Published on: 
Mar-2022

https://pubmed.ncbi.nlm.nih.gov/35148883/ transplant

Transplant Proc. 2022 Feb 8;S0041-1345(22)00063-X.
doi: 10.1016/j.transproceed.2022.01.008.Online ahead of print.

Long-Term Outcome of Portal Vein Stenting After Pediatric Living Donor Liver Transplantation

Takehisa Ueno 1, Chiyoshi Toyama 2, Koichi Deguchi 2, Kazunori Masahata 2, Motonari Nomura 2, Miho Watanabe 2, Masafumi Kamiyama 2, Yuko Tazuke 2, Kazuhiko Bessho 3, Hiroomi Okuyama 2

Abstract

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/34620760/

J Pediatr Gastroenterol Nutr. 2022 Feb 1;74(2):186-191.
doi: 10.1097/MPG.0000000000003316.

Can the Enhanced Liver Fibrosis Score Be Used to Diagnose Children With Liver Fibrosis?

Iben Thusing 1, Steen Antonsen 2, Benjamin Søgaard Hoffmann-Petersen 1, Helene Marlies Rasmussen 1, Per Wittenhagen 1

Abstract

Objectives: The noninvasive Enhanced Liver Fibrosis (ELF) score is used in adults with liver fibrosis as a diagnostic aid. The ELF score combines 3 serum markers of extracellular matrix remodeling and fibrogenesis: hyaluronic acid (HA), the N-terminal pro-peptide of collagen type III (PIIINP), and tissue inhibitor of metalloproteinase-1 (TIMP-1). We aimed to evaluate the clinical use of the ELF score in children.

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/35133671/ NAFLD

Hepatology. 2022 Feb 8.
doi: 10.1002/hep.32403. Online ahead of print.

Randomized Placebo-Controlled Trial of Losartan for Pediatric Nonalcoholic Fatty Liver Disease

Miriam B Vos 1, Mark L Van Natta 2, Niviann M Blondet 3, Srinivasan Dasarathy 4, Mark Fishbein 5, Paula Hertel 6, Ajay K Jain 7, Saul J Karpen 1, Joel E Lavine 8, Saeed Mohammad 5, Laura A Miriel 2, Jean P Molleston 9, Marialena Mouzaki 10, Arun Sanyal 11, Emily P Sharkey 2, Jeffrey B Schwimmer 12, James Tonascia 2, Laura A Wilson 2, Stavra A Xanthakos 10, NASH Clinical Research Network

Abstract

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/34505750/ Covid-19
Pediatr Transplant. 2022 Feb;26(1):e14138.
doi: 10.1111/petr.14138. Epub 2021 Sep 10.

Telemedicine in monitoring pediatric LT patients before and during COVID-19 pandemic

Mirac Musaoğlu 1, Muhammed Yuksel 1 2, Ozlem Mizikoglu 1, Cigdem Arikan 1 2
Free PMC article

Abstract

Background: The delivery of healthcare services by telemedicine decreases costs of traveling for patients, is less time-consuming, and most importantly permits the connection between highly skilled specialists and patients. However, whether the use of telemedicine (text messaging) for LT patients was affected by the COVID-19 pandemic is unknown.

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/35132740/ Liver transplant

Pediatr Transplant. 2022 Feb 7;e14240.
doi: 10.1111/petr.14240. Online ahead of print.

Neurological impairment in children with acute liver failure following liver transplantation-A single-center experience

Kentaro Ide 1 2, Hajime Uchida 3, Seisuke Sakamoto 3, Nao Nishimura 1, Satoshi Nakagawa 1, Tohru Kobayashi 2 4, Shuichi Ito 2, Mureo Kasahara 3

Abstract

Background: Although overall survival of ALF has improved, neurological restoration after recovery from ALF may not always be satisfactory. The purpose of this study was to investigate the occurrence and possible causes of NI in children with ALF following LT.

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/35131781/ Wilson

BMJ Case Rep. 2022 Feb 7;15(2):e246075.
doi: 10.1136/bcr-2021-246075.

Hyperpigmented patch: an uncommon but early marker of Wilson's disease

Lokesh Tiwari 1, Fadila 2, Arnab Ghorui 2

Abstract

Wilson's disease in childhood could present with features ranging from asymptomatic liver disease to acute liver failure and cirrhosis. Neurological manifestations and psychiatric illness occur more commonly in adults and older children. Skin manifestation with Wilson's disease is not frequently reported in literature but could be an early diagnostic clincher. We present a child with hepatic Wilson's disease and skin hyperpigmentation. We aim to highlight the possible importance of skin lesions as an early marker of Wilson's disease.

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/35149641/ Hepatitis C

J Pediatr Gastroenterol Nutr. 2022 Feb 10.
doi: 10.1097/MPG.0000000000003406.Online ahead of print.

Ledipasvir-sofosbuvir in Adolescents with Chronic Hepatitis C and Hematological Malignancies Undergoing Chemotherapy

Manal Hamdy El-Sayed 1, Fatma S Elsayed Ebeid, Abdel-Rahman Zekri, Benedetta Massetto, Kathryn Kersey, Fangqiu Zhang, Anuj Gaggar, Walaa Elsayed, Alaa El-Haddad

Abstract

Objectives: In children with hematological malignancies, chronic HCV infection has been associated with more rapid liver disease progression and higher risk of malignancy relapse due to chemotherapy interruption. We evaluated the safety and efficacy of ledipasvir-sofosbuvir for 12 weeks in these patients.

Published on: 
Feb-2022

https://pubmed.ncbi.nlm.nih.gov/35109890/ PFIC

Orphanet J Rare Dis. 2022 Feb 2;17(1):32.
doi: 10.1186/s13023-022-02177-0.

Impact of progressive familial intrahepatic cholestasis on caregivers: caregiver-reported outcomes from the multinational PICTURE study

Claudia Mighiu 1, Sonia O'Hara 2, Enrico Ferri Grazzi 2, Karen F Murray 3, Jörn M Schattenberg 4, Emily Ventura 5, Melanie Karakaidos 5, Alison Taylor 6, Harpreet Brrang 6, Anil Dhawan 7, Jose Willemse 8, Alan Finnegan 9

Abstract

Published on: 
Feb-2022

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