Event Videos

https://www.ncbi.nlm.nih.gov/pubmed/30465125 Biliary Atresia

World J Pediatr. 2018 Nov 21. doi: 10.1007/s12519-018-0203-1. [Epub ahead of print]
Liver fibrosis in biliary atresia.
Shen WJ1, Chen G1, Wang M1, Zheng S2.

Abstract

BACKGROUND:
Biliary atresia (BA) is the most common cause of obstructive jaundice in infants. Although the Kasai procedure has greatly improved the prognosis, most patients still need liver transplantation (LT) for long-term survival. The pathogenesis of BA has not been fully clarified, and liver fibrosis in BA is far beyond biliary obstructive cirrhosis.

DATA SOURCES:

Published on: 
Nov-2018

https://www.ncbi.nlm.nih.gov/pubmed/30496763 Hepatitis C

J Hepatol. 2018 Nov 26. pii: S0168-8278(18)32545-5. doi: 10.1016/j.jhep.2018.11.013. [Epub ahead of print]
Epidemiology and natural history of hepatitis C virus infection among children and young people.
Modin L1, Arshad A2, Wilkes B3, Benselin J3, Lloyd C2, Irving WL3, Kelly DA2.

Abstract

BACKGROUND:
Chronic hepatitis C virus (HCV) infection is a global health burden. Although HCV infection rarely contributes to morbidity during childhood, the majority of HCV infected children develop chronic HCV with a lifetime risk of liver disease. Little is known about the development of long-term liver disease and treatment effect in patients infected with HCV in childhood.

METHOD:

Published on: 
Nov-2018

https://www.ncbi.nlm.nih.gov/pubmed/30466898 Hepatitis B

Int J Infect Dis. 2018 Nov 19. pii: S1201-9712(18)34565-X. doi: 10.1016/j.ijid.2018.08.024. [Epub ahead of print]
Cost-effectiveness analysis of hepatitis B vaccine booster in children born to HBsAg-positive mothers in rural China.
Wang Y1, Shi JF2, Wang L3, Yan Y4, Yao H5, Dai M6, Chen T7, Qu C8.

Abstract

OBJECTIVE:

Published on: 
Nov-2018

https://www.ncbi.nlm.nih.gov/pubmed/30489487 Liver transplant

Pediatr Crit Care Med. 2018 Nov 26. doi: 10.1097/PCC.0000000000001815. [Epub ahead of print]
Benefits of Early Mobilization After Pediatric Liver Transplantation.
Tsuboi N1, Hiratsuka M1, Kaneko S1, Nishimura N1, Nakagawa S1, Kasahara M2, Kamikubo T3.

Abstract

OBJECTIVE:
To evaluate the impact of early mobilization after pediatric liver transplantation in the PICU.

DESIGN:
A 70-month retrospective before-after study.

SETTING:
Medical and surgical PICU with 20 beds at a tertiary children's hospital.

PATIENTS:
Seventy-five patients 2-18 years old who underwent liver transplantation and could walk before surgery.

INTERVENTION:

Published on: 
Nov-2018

https://www.ncbi.nlm.nih.gov/pubmed/30475212 Hepatitis B
Turk J Gastroenterol. 2018 Nov 26. doi: 10.5152/tjg.2018.18148. [Epub ahead of print]
Lamivudine's efficacy and safety in preventing mother-to-child transmission of hepatitis B: A meta-analysis.
Khalighinejad P1, Alavian SM2, Fesharaki MG3, Jalilianhasanpour R4.

Abstract

BACKGROUND/AIMS:
Mother-to-child transmission (MTCT) is a common transmission mode of hepatitis B virus (HBV). It has been shown that the infection may occur in some infants despite the use of immunoprophylaxis, and many studies have demonstrated the efficacy of antivirals such as lamivudine to reduce such events.

MATERIALS AND METHODS:

Published on: 
Nov-2018

https://www.ncbi.nlm.nih.gov/pubmed/30259895 Autoimmune hepatitis
J Nippon Med Sch. 2018;85(4):241-244. doi: 10.1272/jnms.JNMS.2018_85-38.
An 8-Year-Old Girl with Autoimmune Hepatitis Following Aplastic Anemia.
Nishigori A1, Hatori T2, Asano T1.

Abstract

We herein report a case of severe aplastic anemia diagnosed in an 8-year-old girl with a previous diagnosis of autoimmune hepatitis. We found significantly increased CD8+ and CD68+ cell numbers in her bone marrow, which can induce severe organ damage, refractory to immunosuppressive therapy.

Published on: 
Oct-2018

https://www.ncbi.nlm.nih.gov/pubmed/30479320 Biliary Atresia

Saudi J Gastroenterol. 2018 Nov 27. doi: 10.4103/sjg.SJG_306_18. [Epub ahead of print]
Outcome of biliary atresia among Saudi children: A tertiary care center experience.
Holdar S1, Alsaleem B1, Asery A1, Al-Hussaini A2.

Abstract

BACKGROUND/AIMS:
Data from Western countries indicate that biliary atresia (BA) is the leading cause of end-stage liver disease in children and the most common indication for liver transplantation (LT) in the pediatric population. There is no data on the epidemiology and outcome of BA in Saudi Arabia. The main objective of our study was to understand the clinical and epidemiological characteristics and outcome of BA in the Saudi population.

PATIENTS AND METHODS:

Published on: 
Nov-2018

https://www.ncbi.nlm.nih.gov/pubmed/30281558 Liver transplant

AIDS. 2018 Oct 23;32(16):F13-F19. doi: 10.1097/QAD.0000000000002000.
Living donor liver transplant from an HIV-positive mother to her HIV-negative child: opening up new therapeutic options.

Botha J1, Conradie F2,3, Etheredge H1,3, Fabian J1,3, Duncan M1, Haeri Mazanderani A4,5, Paximadis M4,6, Maher H1, Britz R1, Loveland J1,7, Ströbele B1, Rambarran S1, Mahomed A1,3, Terblanche A1, Beretta M1, Brannigan L1, Pienaar M1, Archibald-Durham L1, Lang A1, Tiemessen CT4,6.

Abstract

OBJECTIVE:
Transplant a liver from an HIV-positive mother to her HIV-negative child to save the child's life.

DESIGN:

Published on: 
Oct-2018

https://www.ncbi.nlm.nih.gov/pubmed/30483543 Cirrhosis
JGH Open. 2017 Oct 31;1(3):92-97. doi: 10.1002/jgh3.12016. eCollection 2017 Nov.
Aggressive nutrition intervention reduces ascites and frequency of paracentesis in malnourished patients with cirrhosis and ascites.
Vidot H1,2, Bowen DG3,2,4, Carey S1, McCaughan GW3,2,4, Allman-Farinelli M5, Shackel NA3,4,6.

Abstract

BACKGROUND AND AIM:

Published on: 
Nov-2018

CLF Intro movie

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