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Acute myeloid leukemia presenting as obstructive jaundice

Indian Pediatr. 2012 May 8;49(5):414-6.

Acute myeloid leukemia presenting as obstructive jaundice.
Rajeswari B, Ninan A, Prasannakumari SN, Parukuttyamma K.
Division of Pediatric Oncology and * Division of Pathology, Regional Cancer Centre, Trivandrum, India. Correspondence to: Binitha Rajeswari, Lecturer, Division of Pediatric Oncology, Regional Cancer Centre, Trivandrum, India. rbinitha@yahoo.co.in.

Abstract
Jaundice as a presenting feature of pediatric acute myeloid leukemia is rare. We report two cases of AML who presented with obstructive jaundice, one with a malignant stricture at the common bile duct and other with a granulocytic sarcoma obstructing the bile duct. The prognosis is poor in these patients.

Published on: 
May-2012

Endoscopic retrograde cholangiopancreatography in neonatal cholestasis

J Pediatr Gastroenterol Nutr. 2012 Aug;55(2):142-5.

Endoscopic retrograde cholangiopancreatography in neonatal cholestasis.
Shteyer E, Wengrower D, Benuri-Silbiger I, Gozal D, Wilschanski M, Goldin E.
*Pediatric Gastroenterology Unit †Department of Gastroenterology ‡Division of Anesthesiology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Abstract

BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is not as widely used in children as in adults and is performed in few specialized centers. The aim of the present study was to review the experience of ERCP in children younger than 3 months in a national referral center.

Published on: 
Aug-2012
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Evaluation of risk factors for bleeding after liver biopsy in children

J Pediatr Gastroenterol Nutr. 2012 Jul;55(1):82-7.

Evaluation of risk factors for bleeding after liver biopsy in children.
Westheim BH, Østensen AB, Aagenæs I, Sanengen T, Almaas R.
Department of Pediatric Research, Rikshospitalet, Oslo University Hospital, Oslo, Norway.

Abstract

OBJECTIVES: Acetylsalicylic acid is used in liver-transplanted children to prevent thrombosis of the hepatic artery. We evaluated whether acetylsalicylic acid and other risk factors were associated with bleeding after percutaneous liver biopsy.

Published on: 
Jul-2012
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Glycogen Storage Disease 1a with Piebaldism

http://www.indianpediatrics.net/mar2012/mar-235-145.htm

Glycogen Storage Disease 1a with Piebaldism
Bhaswati Ghoshal, Nirmalya Sarkar, Mala Bhattacharjee and Rabindra Bhattacharjee
From the Departments of Pediatrics and Cardiology, Calcutta National Medical College, Kolkata, India.
Correspondence to: Bhaswati Ghoshal, Assistant Professor, Department of Pediatric Medicine, Calcutta National Medical College Hospital, Kolkata, India.
Email: bhaswatighoshalmailme@yahoo.com
Received: March 09, 2010;
Initial review: May 10, 2010;
Accepted: November 03, 2010.

Published on: 
Mar-2012
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Clofibrate for Unconjugated Hyperbilirubinemia in Neonates

http://www.indianpediatrics.net/jan2012/35.pdf

Clofibrate for Unconjugated Hyperbilirubinemia in Neonates.

A Systematic Review
TAO XIONG, DAPENG CHEN, ZHOUJIN DUAN, YI QU AND DEZHI MU*
From the Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China and *Department of Neurology and Pediatrics, Newborn Brain Research Institute, University of California, San Francisco, California, USA.
Correspondence to: Dezhi Mu, Department of Pediatrics, West China Second University Hospital, Sichuan University, China.
dezhi.mu@ucsf.edu

Objective: To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in neonates.

Published on: 
Jan-2012
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Parenteral plant sterols and intestinal failure-associated liver disease in neonates

J Pediatr Gastroenterol Nutr. 2012 Jun;54(6):803-11.

Parenteral plant sterols and intestinal failure-associated liver disease in neonates.
Kurvinen A, Nissinen MJ, Andersson S, Korhonen P, Ruuska T, Taimisto M, Kalliomäki M, Lehtonen L, Sankilampi U, Arikoski P, Saarela T, Miettinen TA, Gylling H, Pakarinen MP.
Section of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland. annika.kurvinen@helsinki.fi

Abstract

OBJECTIVES: We prospectively evaluated incidence of prolonged (>28 days) parenteral nutrition (PN), associated complications, and significance of parenteral plant sterols (PS) in neonatal intestinal failure-associated liver disease (IFALD) compared with children.

Published on: 
Jun-2012
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Chinese Children With Chronic Intrahepatic Cholestasis and High γ-Glutamyl Transpeptidase: Clinical Features and Association With ABCB4 Mutations

J Pediatr Gastroenterol Nutr. 2012 Aug;55(2):150-6.

Chinese Children With Chronic Intrahepatic Cholestasis and High γ-Glutamyl Transpeptidase: Clinical Features and Association With ABCB4 Mutations.
Fang LJ, Wang XH, Knisely AS, Yu H, Lu Y, Liu LY, Wang JS.
*Center for Pediatric Liver Diseases, Children's Hospital of Fudan University, Shanghai, China †Institute of Liver Studies, King's College Hospital Denmark Hill, London, UK.

Abstract

OBJECTIVE:  The aims of the present study was to study the significance of ABCB4 mutations in mainland Chinese children with chronic intrahepatic cholestasis and to correlate genetic findings with clinical features and response to ursodeoxycholic acid (UDCA) therapy.

Published on: 
Aug-2012
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Predictors of clinically significant upper gastrointestinal hemorrhage among children with hematemesis

J Pediatr Gastroenterol Nutr. 2012 Jun;54(6):737-43.

Predictors of clinically significant upper gastrointestinal hemorrhage among children with hematemesis.
Freedman SB, Stewart C, Rumantir M, Thull-Freedman JD.
Division of Paediatric Emergency Medicine, The Hospital for Sick Children, Toronto, ON, Canada. stephen.freedman@sickkids.ca

Abstract

OBJECTIVES: The aim of the study was to determine the proportion of children with hematemesis who experience a clinically significant upper gastrointestinal hemorrhage (UGIH) and to identify variables predicting their occurrence.

Published on: 
Jun-2012
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