Event Videos

https://pubmed.ncbi.nlm.nih.gov/37013855/ liver transplant

Pediatr Transplant. 2023 Apr 4;e14524.
doi: 10.1111/petr.14524. Online ahead of print.

Perioperative risk factors for neurological impairment in infants with acute liver failure following liver transplantation

Kentaro Ide 1 2, Hajime Uchida 3, Seisuke Sakamoto 3, Itaru Hayakawa 4, Satoshi Nakagawa 1, Tohru Kobayashi 2 5, Shuichi Ito 2, Mureo Kasahara 3

Abstract
Background: Neurological impairment is not rare in infants with acute liver failure (ALF). This study aimed to investigate the perioperative risk factors for neurological impairment following liver transplantation (LT) in infantile ALF.

Published on: 
Apr-2023

https://pubmed.ncbi.nlm.nih.gov/37237284/ choledochal cyst

BMC Pediatr. 2023 May 26;23(1):266.
doi: 10.1186/s12887-023-03994-3.

Management of complicated choledochal cyst in children: ultrasound-guided percutaneous external drainage and subsequent definitive operation

Jiayu Yan # 1, Chuankai Lv # 1, Dan Zhang # 1, Mingkang Zheng # 2, Chunhui Peng 1, Wenbo Pang 1, Wei Chen 1, Siwei Wang 3, Xiaoman Wang 4, Yajun Chen 5

Abstract

Objective: The purpose of this study was to analyze the outcomes of the combination of ultrasound (US)-guided percutaneous external drainage and subsequent definitive operation to manage complicated choledochal cyst in children.

Published on: 
May-2023

https://pubmed.ncbi.nlm.nih.gov/37019333/ Genetic

J Pediatr. 2023 Apr 3;113408.
doi: 10.1016/j.jpeds.2023.113408. Online ahead of print.

Combining Panel-Based Next-Generation Sequencing and Exome Sequencing for Genetic Liver Diseases

Chi-Bo Chen 1, Jacob Shujui Hsu 2, Pei-Lung Chen 3, Jia-Feng Wu 1, Huei-Ying Li 4, Bang-Yu Liou 1, Mei-Hwei Chang 1, Yen-Hsuan Ni 5, Wuh-Liang Hwu 6, Yin-Hsiu Chien 6, Yen-Yin Chou 7, Yao-Jong Yang 7, Ni-Chung Lee 8, Huey-Ling Chen 9

Abstract

Objectives: To determine how advanced genetic analysis methods may help in clinical diagnosis.

Published on: 
Apr-2023

https://pubmed.ncbi.nlm.nih.gov/37213043/

Indian J Gastroenterol. 2023 May 22.
doi: 10.1007/s12664-023-01350-y. Online ahead of print.

Clinical profile and outcomes of pediatric scrub typhus associated with elevated hepatic transaminases

Dinesh Kumar Narayanasamy 1, Thirunavukkarasu Arun Babu 2, Jean Fredrick 3, Devi Kittu 4

Abstract

Background: Hepatic transaminase (HT) elevation is frequently seen in children with scrub typhus (ST), but the clinical implication of this common finding is not known.

Objective: To describe the clinical profile and outcome of pediatric ST with elevated hepatic transaminase.

Published on: 
May-2023

https://pubmed.ncbi.nlm.nih.gov/37021791/ NAFLD

Hepatology. 2023 Apr 10.
doi: 10.1097/HEP.0000000000000383. Online ahead of print.

Global and national prevalence of nonalcoholic fatty liver disease in adolescents: an analysis of the global burden of disease study 2019

Phillipp Hartmann 1 2, Xinlian Zhang 3, Rohit Loomba 4 5 6, Bernd Schnabl 6 7

Abstract

Background and aims: N onalcoholic fatty liver disease (NAFLD) in adolescents is an increasing health crisis worldwide but its exact global, continental, and national prevalence, its relationship with other metabolic conditions and the human development index (HDI) globally are not known.

Published on: 
Apr-2023

https://pubmed.ncbi.nlm.nih.gov/37229749/ Alpha1 antitrypsin
J Pediatr Gastroenterol Nutr. 2023 May 25.
doi: 10.1097/MPG.0000000000003845.Online ahead of print.

Presence of Alpha 1 Antitrypsin risk variants is not associated with histologic severity of pediatric NAFLD

Maya Zahid Khan 1, Corie Klepper 2, Sarah Orkin 2 3, Ana Catalina Arce-Clachar 2 3, Kristen Bramlage 2 3, Lin Fei 2 3, Alexander Miethke 2 3, Rohit Kohli 4, Stavra Xanthakos 2 3, Marialena Mouzaki 2 3

Abstract
Background: Among adults with nonalcoholic fatty liver disease (NAFLD), alpha-1 antitrypsin (A1AT) heterozygosity has been linked to advanced liver disease; pediatric data remain unclear.

Published on: 
May-2023

https://pubmed.ncbi.nlm.nih.gov/37058274/ Biliary atresia

Indian J Gastroenterol. 2023 Apr 14.
doi: 10.1007/s12664-022-01328-2. Online ahead of print.

Treatment of intractable cholangitis in children with biliary atresia: Impact on outcome

Supriya Mahajan 1, Bikrant Bihari Lal 1, Pankaj Kumar 2, Piyush Upadhyay 1, Amar Mukund 3, Vikrant Sood 1, Rajeev Khanna 1, Seema Alam 4

Abstract

Objectives: To evaluate the response and outcome with prolonged intravenous antibiotics including home-based intravenous antibiotics in children with intractable cholangitis (IC) after Kasai portoenterostomy (KPE) for biliary atresia (BA).

Published on: 
Apr-2023

https://pubmed.ncbi.nlm.nih.gov/37013431/ NAFLD

Curr Pediatr Rev. 2023 Apr 3.
doi: 10.2174/1573396319666230403121805.Online ahead of print.

Metabolic Associated Fatty Liver Disease in children and adolescents: mechanisms of a silent epidemic and therapeutic options

Antonella Mosca 1, Luca Della Volpe 1, Maria Rita Sartorelli 2, Donatella Comparcola 2, Silvio Veraldi 1, Anna Alisi 3, Giuseppe Maggiore 1

Abstract

Published on: 
Apr-2023

https://pubmed.ncbi.nlm.nih.gov/37077330/ liver transplant

Front Pediatr. 2023 Mar 30;11:1174357.
doi: 10.3389/fped.2023.1174357. eCollection 2023.

Subclinical cardiac abnormalities in children with biliary atresia correlate with outcomes after liver transplantation

Tingting Li 1, Xinzhe Wei 2 3, Xiaoye Hao 4, Xuying Ye 5, Chao Li 5, Qi Li 6, Zhuqing Li 6, Wei Gao 2 3, Chengzhi Lu 5

Abstract

Published on: 
Apr-2023

CLF Intro movie

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