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Metabolic Associated Fatty Liver Disease in children and adolescents: mechanisms of a silent epidemic and therapeutic options https://pubmed.ncbi.nlm.nih.gov/37013431/ NAFLD Curr Pediatr Rev. 2023 Apr 3. doi: 10.2174/1573396319666230403121805.Online ahead of print. Metabolic Associated Fatty Liver Disease in children and adolescents: mechanisms of a silent epidemic and therapeutic options Antonella Mosca 1, Luca Della Volpe 1, Maria Rita Sartorelli 2, Donatella Comparcola 2, Silvio Veraldi 1, Anna Alisi 3, Giuseppe Maggiore 1 Abstract Published on: Apr-2023 Read more	Subclinical cardiac abnormalities in children with biliary atresia correlate with outcomes after liver transplantation https://pubmed.ncbi.nlm.nih.gov/37077330/ liver transplant Front Pediatr. 2023 Mar 30;11:1174357. doi: 10.3389/fped.2023.1174357. eCollection 2023. Subclinical cardiac abnormalities in children with biliary atresia correlate with outcomes after liver transplantation Tingting Li 1, Xinzhe Wei 2 3, Xiaoye Hao 4, Xuying Ye 5, Chao Li 5, Qi Li 6, Zhuqing Li 6, Wei Gao 2 3, Chengzhi Lu 5 Abstract Published on: Apr-2023 Read more
Perioperative risk factors for neurological impairment in infants with acute liver failure following liver transplantation https://pubmed.ncbi.nlm.nih.gov/37013855/ liver transplant Pediatr Transplant. 2023 Apr 4;e14524. doi: 10.1111/petr.14524. Online ahead of print. Perioperative risk factors for neurological impairment in infants with acute liver failure following liver transplantation Kentaro Ide 1 2, Hajime Uchida 3, Seisuke Sakamoto 3, Itaru Hayakawa 4, Satoshi Nakagawa 1, Tohru Kobayashi 2 5, Shuichi Ito 2, Mureo Kasahara 3 Abstract Background: Neurological impairment is not rare in infants with acute liver failure (ALF). This study aimed to investigate the perioperative risk factors for neurological impairment following liver transplantation (LT) in infantile ALF. Published on: Apr-2023 Read more	Plasticity between ILC2 subsets and amphiregulin expression regulate epithelial repair in biliary atresia https://pubmed.ncbi.nlm.nih.gov/37078450/ biliary atresia Hepatology. 2023 Apr 21. doi: 10.1097/HEP.0000000000000418. Online ahead of print . Plasticity between ILC2 subsets and amphiregulin expression regulate epithelial repair in biliary atresia Abigail E Russi 1 2, Pranavkumar Shivakumar 1 2, Zhenhua Luo 3, Jorge Bezerra 4 Abstract Published on: Apr-2023 Read more
Combining Panel-Based Next-Generation Sequencing and Exome Sequencing for Genetic Liver Diseases https://pubmed.ncbi.nlm.nih.gov/37019333/ Genetic J Pediatr. 2023 Apr 3;113408. doi: 10.1016/j.jpeds.2023.113408. Online ahead of print. Combining Panel-Based Next-Generation Sequencing and Exome Sequencing for Genetic Liver Diseases Chi-Bo Chen 1, Jacob Shujui Hsu 2, Pei-Lung Chen 3, Jia-Feng Wu 1, Huei-Ying Li 4, Bang-Yu Liou 1, Mei-Hwei Chang 1, Yen-Hsuan Ni 5, Wuh-Liang Hwu 6, Yin-Hsiu Chien 6, Yen-Yin Chou 7, Yao-Jong Yang 7, Ni-Chung Lee 8, Huey-Ling Chen 9 Abstract Objectives: To determine how advanced genetic analysis methods may help in clinical diagnosis. Published on: Apr-2023 Read more	Focal Nodular Hyperplasia in the Pediatric Population: A Multicenter Experience https://pubmed.ncbi.nlm.nih.gov/37082924/ Pediatr Dev Pathol. 2023 Apr 21;10935266231167489. doi: 10.1177/10935266231167489.Online ahead of print. Focal Nodular Hyperplasia in the Pediatric Population: A Multicenter Experience Iván A González 1, Donghai Wang 2, Maria Cristina Pacheco 3, Xuchen Zhang 2, Pierre Russo 1 Abstract Background: Focal nodular hyperplasia (FNH) is a benign liver lesion classically presenting in young females. In children, FNH is rare and its detailed clinicopathologic characteristics remain largely unknown. Furthermore, there are no studies comparing pediatric FNH features to those presenting in adults. Published on: Apr-2023 Read more
Global and national prevalence of nonalcoholic fatty liver disease in adolescents: an analysis of the global burden of disease study 2019 https://pubmed.ncbi.nlm.nih.gov/37021791/ NAFLD Hepatology. 2023 Apr 10. doi: 10.1097/HEP.0000000000000383. Online ahead of print. Global and national prevalence of nonalcoholic fatty liver disease in adolescents: an analysis of the global burden of disease study 2019 Phillipp Hartmann 1 2, Xinlian Zhang 3, Rohit Loomba 4 5 6, Bernd Schnabl 6 7 Abstract Background and aims: N onalcoholic fatty liver disease (NAFLD) in adolescents is an increasing health crisis worldwide but its exact global, continental, and national prevalence, its relationship with other metabolic conditions and the human development index (HDI) globally are not known. Published on: Apr-2023 Read more	An Open Label, Randomized, Multicenter Study of Elafibranor in Children with Nonalcoholic Steatohepatitis https://pubmed.ncbi.nlm.nih.gov/37084342/ NAFLD J Pediatr Gastroenterol Nutr. 2023 Apr 21. doi: 10.1097/MPG.0000000000003796.Online ahead of print. An Open Label, Randomized, Multicenter Study of Elafibranor in Children with Nonalcoholic Steatohepatitis Nidhi P Goyal 1 2, Ali Mencin 3, Kimberly P Newton 1 2, Janis Durelle 1, Carissa Carrier 1, Patricia Ugalde-Nicalo 1, Benoit Noel 1, Julie Mouton 4, Dawn Vargas 1, David Magrez 4, Bachirou Tadde 4, Pascal Birman 4, Brookie M Best 5 6, Carol Addy 1, Jeffrey B Schwimmer 1 2 Abstract Published on: Apr-2023 Read more
Treatment of intractable cholangitis in children with biliary atresia: Impact on outcome https://pubmed.ncbi.nlm.nih.gov/37058274/ Biliary atresia Indian J Gastroenterol. 2023 Apr 14. doi: 10.1007/s12664-022-01328-2. Online ahead of print. Treatment of intractable cholangitis in children with biliary atresia: Impact on outcome Supriya Mahajan 1, Bikrant Bihari Lal 1, Pankaj Kumar 2, Piyush Upadhyay 1, Amar Mukund 3, Vikrant Sood 1, Rajeev Khanna 1, Seema Alam 4 Abstract Objectives: To evaluate the response and outcome with prolonged intravenous antibiotics including home-based intravenous antibiotics in children with intractable cholangitis (IC) after Kasai portoenterostomy (KPE) for biliary atresia (BA). Published on: Apr-2023 Read more	Recent Increase in Incidence of Severe Acute Hepatitis of Unknown Etiology in Children Is Associated with Infection with Adenovirus and Other Non-hepatotropic Viruses https://pubmed.ncbi.nlm.nih.gov/37088181/ hepatitis J Pediatr. 2023 Apr 21;113439. doi: 10.1016/j.jpeds.2023.113439. Online ahead of print. Recent Increase in Incidence of Severe Acute Hepatitis of Unknown Etiology in Children Is Associated with Infection with Adenovirus and Other Non-hepatotropic Viruses Anna L Peters 1, Seung Kim 2, Reena Mourya 2, Akihiro Asai 3, Amy Taylor 3, Michael Rogers 3, Kathleen Campbell 3, Lin Fei 4, Alexander Miethke 3, William F Balistreri 3, Jorge A Bezerra 5 Abstract Objective: To evaluate whether the nature and severity of non-A-E severe acute hepatitis (NAESAH) in children noted by the WHO from late 2021 through early 2022 was indeed increased in 2021-2022 compared with prior years. Published on: Apr-2023 Read more

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