Event Videos

https://pubmed.ncbi.nlm.nih.gov/36694298/ Liver transplant

Case Reports

Pediatr Transplant. 2023 Jan 24;e14473.
doi: 10.1111/petr.14473. Online ahead of print.

Late airway complications following pediatric liver transplantation: A case series
Vivek Rajasekaran 1 2, Craig McCaffer 3, Jonathan Bishop 1, Graeme Van Der Meer 3, Edward C Toll 3, Helen Evans 1 2

Abstract
Background: Late airway complications, as consequence of immunosuppression following pediatric liver transplantation are uncommonly reported.

Methods: In this retrospective case series, we describe two young children presenting with symptoms of airway obstruction, secondary to differing pathologies in the supraglottic airway, as a result of immunosuppression following liver transplantation.

Published on: 
Jan-2023

https://pubmed.ncbi.nlm.nih.gov/36511610/ wilson disease

Turk J Gastroenterol. 2022 Dec 13.

doi: 10.5152/tjg.2022.22216. Online ahead of print.

Is Prolonged Copper Restriction Needed in Pediatric Wilson's Disease?

Hayriye Hizarcıoğlu-Gülşen 1, Pınar Şimşek Onat 1, Damla Yıldırım 2, Duygu Demirtaş 3, Meryem S Boyraz 4, Mehmet A Göktaş 4, Hülya Demir 1, Hasan Özen 1, İnci Nur Saltık Temizel 1

Abstract

Published on: 
Dec-2022

https://pubmed.ncbi.nlm.nih.gov/36694381/ Covid-19
Obesity (Silver Spring). 2023 Jan 24.
doi: 10.1002/oby.23728. Online ahead of print.

Rising NAFLD and Metabolic Severity During the Sars-CoV-2 Pandemic among Children with Obesity in the United States

Aaron L Slusher 1, Pamela Hu 1, Stephanie Samuels 1, Fuyuze Tokoglu 2, Jessica Lat 1, Zhongyao Li 1, Michele Alguard 1, Jordan Strober 3, Daniel Vatner 3, Veronika Shabanova 1, Sonia Caprio 1

Abstract
Background: Non-alcoholic fatty liver disease (NAFLD), the most common liver disease among youth with obesity, precedes more severe metabolic and liver diseases. However, the impact of the Sars-CoV-2 global pandemic on the prevalence and severity of NAFLD and the associated metabolic phenotype among youth with obesity is unknown.

Published on: 
Jan-2023

https://pubmed.ncbi.nlm.nih.gov/36541813/ biliary atresia

Pediatr Int. 2022 Dec 21;e15454.
doi: 10.1111/ped.15454. Online ahead of print.

The presence of high-risk varices after sclerotherapy in biliary atresia

Shinya Yokoyama 1, Yoji Ishizu 1, Takashi Honda 1, Norihiro Imai 1, Takanori Ito 1, Kenta Yamamoto 1, Chiyoe Shirota 2, Takahisa Tainaka 2, Wataru Sumida 2, Satoshi Makita 2, Aitaro Takimoto 2, Yoichi Nakagawa 2, Shunya Takada 2, Masatoshi Ishigami 1, Hiroo Uchida 2, Hiroki Kawashima 1

Abstract

Published on: 
Dec-2022

https://pubmed.ncbi.nlm.nih.gov/36695617/ liver transplant

Am J Transplant. 2023 Jan;23(1):26-36.
doi: 10.1016/j.ajt.2022.09.004. Epub 2023 Jan 11.

Innate immune cell dysfunction and systemic inflammation in children with chronic liver diseases undergoing transplantation.

Krupa R Mysore 1, Sunil Kannanganat 2, Jeremy M Schraw 3, Philip J Lupo 3, John A Goss 4, Kenneth D R Setchell 5, Farrah Kheradmand 6, Xian C Li 7, Benjamin L Shneider 8

Abstract

Published on: 
Jan-2023

https://pubmed.ncbi.nlm.nih.gov/36550572/ PFIC

Review

Orphanet J Rare Dis. 2022 Dec 22;17(1):445.
doi: 10.1186/s13023-022-02597-y.

Clinical and genetic characterization of pediatric patients with progressive familial intrahepatic cholestasis type 3 (PFIC3): identification of 14 novel ABCB4 variants and review of the literatures

Rong Chen # 1, Feng-Xia Yang # 2, Yan-Fang Tan 3, Mei Deng 1, Hua Li 1, Yi Xu 2, Wen-Xian Ouyang 4, Yuan-Zong Song 5

Abstract

Background: Progressive familial intrahepatic cholestasis type 3 (PFIC3) is an autosomal recessive disease caused by pathogenic variants of the gene ABCB4. This study aimed to investigate the ABCB4 genotypic and the clinical phenotypic features of PFIC3 patients.

Published on: 
Dec-2022

https://pubmed.ncbi.nlm.nih.gov/36705669/ liver transplant

J Pediatr Gastroenterol Nutr. 2023 Jan 26.
doi: 10.1097/MPG.0000000000003707. Online ahead of print.

Protocol biopsies in pediatric liver transplantation recipients improve graft histology and personalize immunosuppression

Eva Karbaum 1, Sören Weidemann 2, Enke Grabhorn 1, Lutz Fischer 3, Uta Herden 3, Jun Oh 1, Andrea Briem-Richter 1, Dorothee Krebs-Schmitt 1

Abstract
Objectives: Protocol liver biopsies (PLB) are part of the follow-up program at many pediatric liver transplant centers, but the impact on clinical decision-making and allograft histology following adjustments of immunosuppression (IS) after PLB has not been thoroughly analyzed.

Published on: 
Jan-2023

https://pubmed.ncbi.nlm.nih.gov/36708813/ Autoimmune hepatitis

J Hepatol. 2023 Jan 25;S0168-8278(23)00025-9.
doi: 10.1016/j.jhep.2023.01.013. Online ahead of print.

Long-term outcomes of patients with type 1 or 2 autoimmune hepatitis presenting in childhood

Giuseppe Maggiore 1, Olivier Bernard 2, Antonella Mosca 3, Eric Ballot 4, Catherine Johanet 4, Emmanuel Jacquemin 5

Abstract
Background & aims: In children with autoimmune hepatitis, issues include the particularities of type 2 hepatitis regarding outcome, the possibility of and criteria for attempting withdrawal of treatment and the long-term outcome. We report our experience on these issues.

Published on: 
Jan-2023

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