Success Stories

Event Videos

Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial https://pubmed.ncbi.nlm.nih.gov/35780807/ PFIC Lancet Gastroenterol Hepatol. 2022 Jun 30;S2468-1253(22)00093-0. doi: 10.1016/S2468-1253(22)00093-0. Online ahead of print. Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial PMID: 35780807 DOI: 10.1016/S2468-1253(22)00093-0 Abstract Background: Progressive familial intrahepatic cholestasis (PFIC) is a group of inherited paediatric liver diseases resulting from mutations in genes that impact bile secretion. We aimed to evaluate the effects of odevixibat, an ileal bile acid transporter inhibitor, versus placebo in children with PFIC. Published on: Jun-2022 Read more	The benefit of probiotics in pediatric non-alcoholic fatty liver disease: a meta-analysis of randomized control trials https://pubmed.ncbi.nlm.nih.gov/35758473/ NAFLD J Pediatr Gastroenterol Nutr. 2022 Jun 27. doi: 10.1097/MPG.0000000000003537.Online ahead of print. The benefit of probiotics in pediatric non-alcoholic fatty liver disease: a meta-analysis of randomized control trials Νikolaos Gkiourtzis 1 2, Georgios Kalopitas 3, Andreas Vadarlis 3 4, Dimitra Rafailia Bakaloudi 2, Georgios Dionysopoulos 2, Evangelia Karanika 2, Eirini Tsekitsidi 2, Michail Chourdakis 2 Abstract Objectives: We conducted a systematic review and meta-analysis to provide a summary of the current literature about the efficacy of probiotics in pediatric non-alcoholic fatty liver disease (NAFLD). Published on: Jun-2022 Read more
Diagnosis, treatment, and prevention of severe acute hepatitis of unknown etiology in children https://pubmed.ncbi.nlm.nih.gov/35771382/ hepatitis Review World J Pediatr. 2022 Jun 30;1-7. doi: 10.1007/s12519-022-00581-x.Online ahead of print. Ying-Hu Chen 1, Jin-Gan Lou 2, Zi-Hao Yang 3, Qing-Jiang Chen 4, Chun-Zhen Hua 1, Sheng Ye 3, Chen-Mei Zhang 3, Jie Chen 2, Zong-Wei Huang 4, Jin-Dan Yu 2, Zhi-Gang Gao 5, Qiang Shu 6 Affiliations expand PMID: 35771382 PMCID: PMC9244883 DOI: 10.1007/s12519-022-00581-x Free PMC article Abstract Published on: Jun-2022 Read more	Severe Hepatitis in Pediatric Coronavirus Disease 2019 https://pubmed.ncbi.nlm.nih.gov/35149651/ hepatitis J Pediatr Gastroenterol Nutr. 2022 May 1;74(5):631-635. doi: 10.1097/MPG.0000000000003404. Severe Hepatitis in Pediatric Coronavirus Disease 2019 Swati Antala 1, Tamir Diamond 2, Larry K Kociolek 3, Amit A Shah 2, Catherine A Chapin 1 Abstract Published on: May-2022 Read more
Association between alanine aminotransferase as surrogate of fatty liver disease and physical activity and sedentary time in adolescents with obesity https://pubmed.ncbi.nlm.nih.gov/35771354/ NAFLD Eur J Pediatr. 2022 Jun 30. doi: 10.1007/s00431-022-04539-z. Online ahead of print. Association between alanine aminotransferase as surrogate of fatty liver disease and physical activity and sedentary time in adolescents with obesity Valérie Julian 1 2, Peter Bergsten 3 4 5, Gael Ennequin 6, Anders Forslund 4 5, Hakan Ahlstrom 7 8, Iris Ciba 4 5, Marie Dahlbom 4 5, Dieter Furthner 9 10, Julian Gomahr 11 10, Joel Kullberg 7 8, Katharina Maruszczak 11 10, Katharina Morwald 11 10, Roger Olsson 5, Thomas Pixner 9 10, Anna Schneider 11 10, Bruno Pereira 12, Suzanne Ring-Dimitriou 13, David Thivel 6, Daniel Weghuber 11 10 PMID: 35771354 DOI: 10.1007/s00431-022-04539-z Abstract Published on: Jun-2022 Read more	PRESENTATION, MANAGEMENT AND OUTCOME OF CONGENITAL PORTOSYSTEMIC SHUNTS IN CHILDREN: THE BOSTON CHILDREN'S HOSPITAL EXPERIENCE https://pubmed.ncbi.nlm.nih.gov/35442217/ J Pediatr Gastroenterol Nutr. 2022 May 30. doi: 10.1097/MPG.0000000000003450.Online ahead of print. PRESENTATION, MANAGEMENT AND OUTCOME OF CONGENITAL PORTOSYSTEMIC SHUNTS IN CHILDREN: THE BOSTON CHILDREN'S HOSPITAL EXPERIENCE Doaa M Fahmy 1 2, Paul D Mitchell 3, Maureen M Jonas 1 Abstract Objectives: Congenital portosystemic shunts (CPSS) are rare vascular malformations. We describe presentations, complications, associations, and outcomes of CPSS at Boston Children's Hospital (BCH). Methods: This was a retrospective review of children with CPSS at BCH from 2000-2020. Published on: May-2022 Read more
Education and Psychosocial Factors Predict Odds of Death After Transfer to Adult Healthcare in Pediatric Liver Transplant Patients https://pubmed.ncbi.nlm.nih.gov/35767565/ Liver transplant J Pediatr Gastroenterol Nutr. 2022 Jun 27. doi: 10.1097/MPG.0000000000003549.Online ahead of print. Education and Psychosocial Factors Predict Odds of Death After Transfer to Adult Healthcare in Pediatric Liver Transplant Patients James P Stevens 1 2, Scott Gillespie 1, Lori Hall 2, Julia Tisheh 1, Ryan Ford 3, Nitika A Gupta 1 2 PMID: 35767565 DOI: 10.1097/MPG.0000000000003549 Abstract Objective: To analyze demographic, psychosocial and clinical factors in pediatric liver transplant recipients for their association with death or loss to follow-up in adulthood. We aimed to better understand known health disparities in transplant outcomes and identify potentially modifiable risk factors prior to transfer. Published on: Jun-2022 Read more	Nonalcoholic Fatty Liver Disease Risk and Histologic Severity are Associated with Genetic Polymorphisms in Children https://pubmed.ncbi.nlm.nih.gov/35560106/ NAFLD Hepatology. 2022 May 13. doi: 10.1002/hep.32570. Online ahead of print. Nonalcoholic Fatty Liver Disease Risk and Histologic Severity are Associated with Genetic Polymorphisms in Children Nidhi P Goyal 1 2, Sara B Rosenthal 3, Chanod Nasamran 3, Cynthia A Behling 4, Jorge E Angeles 1, Mark H Fishbein 5, Kathryn E Harlow 6, Ajay K Jain 7, Jean P Molleston 8, Kimberly P Newton 1 2, Patricia Ugalde-Nicalo 1, A Xanthankos 9, Katherine Yates 10, Nicholas J Schork 11 12, Kathleen M Fisch 3, Jeffrey B Schwimmer 1 2, N. A. S. H. Clinical Research Network Abstract Published on: May-2022 Read more
Autoimmune Antibodies in Children and Adolescents with Nonalcoholic Fatty Liver Disease https://pubmed.ncbi.nlm.nih.gov/35758506/ Autoimmune hepatitis J Pediatr Gastroenterol Nutr. 2022 Jun 27. doi: 10.1097/MPG.0000000000003534.Online ahead of print. Autoimmune Antibodies in Children and Adolescents with Nonalcoholic Fatty Liver Disease Taisa Kohut 1, Amit Shah 2, Pierre Russo 3, Jennifer Panganiban 2 PMID: 35758506 DOI: 10.1097/MPG.0000000000003534 Abstract Objectives: The clinical significance of autoantibody positivity in nonalcoholic fatty liver disease (NALD) in the absence of autoimmune hepatitis (AIH) remains uncertain. We aimed to determine the prevalence of autoantibodies in a pediatric cohort with biopsy-proven NAFLD and investigate the association between autoantibodies and NAFLD histologic grade. Published on: Jun-2022 Read more	Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults https://pubmed.ncbi.nlm.nih.gov/35577029/ hepatoblastoma J Hepatol. 2022 May 13;S0168-8278(22)00275-6. doi: 10.1016/j.jhep.2022.04.035.Online ahead of print. Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults Published on: May-2022 Read more

CLF Intro movie

SMS requests to

9224791366

Ask The Expert

Pediatric Liver Specialists in India

Centres offering Genetic Testing for Pediatric Liver Diseases

Financial Aid Offered by Trusts

Follow us on:

Facebook Twitter YouTube