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One-Year Outcomes after Ledipasvir/Sofosbuvir Treatment of Chronic Hepatitis C in Teenagers with and without Significant Liver Fibrosis-A Case Series Report https://pubmed.ncbi.nlm.nih.gov/34452383/ hepatitis c Viruses. 2021 Jul 31;13(8):1518. doi: 10.3390/v13081518. One-Year Outcomes after Ledipasvir/Sofosbuvir Treatment of Chronic Hepatitis C in Teenagers with and without Significant Liver Fibrosis-A Case Series Report Maria Pokorska-Śpiewak 1 2, Anna Dobrzeniecka 2, Magdalena Marczyńska 1 2 Abstract Published on: Aug-2021 Read more	Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia https://pubmed.ncbi.nlm.nih.gov/34392560/ Biliary atresia Hepatology. 2021 Aug 15. doi: 10.1002/hep.32107. Online ahead of print. Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia Surya P Amarachintha 1, Reena Mourya 1, Hiroaki Ayabe 1, Li Yang 1, Zhenhua Luo 2, Xiaofeng Li 3, Unmesha Thanekar 1, Pranavkumar Shivakumar 1 4, Jorge A Bezerra 1 4 Abstract Background & aims: Biliary atresia is a severe inflammatory and fibrosing cholangiopathy of neonates of unknown etiology. The onset of cholestasis at birth implies a prenatal onset of liver dysfunction. Aim: To investigate the mechanisms linked to abnormal cholangiocyte development. Published on: Aug-2021 Read more
Domino transplantation for pediatric liver recipients: Obstacles, challenges, and successes https://pubmed.ncbi.nlm.nih.gov/34448327/ liver transplant Review Pediatr Transplant. 2021 Aug 27;e14114. doi: 10.1111/petr.14114.Online ahead of print. Domino transplantation for pediatric liver recipients: Obstacles, challenges, and successes Vikram K Raghu 1, Peter D Carr-Boyd 2, James E Squires 1, Jerry Vockley 3, Nicolas Goldaracena 4, George V Mazariegos 2 Abstract Published on: Aug-2021 Read more	Malnutrition in Pediatric Chronic Cholestatic Disease: An Up-to-Date Overview https://pubmed.ncbi.nlm.nih.gov/34444944/ Cholestatic liver disease Review Nutrients. 2021 Aug 13;13(8):2785. doi: 10.3390/nu13082785. Malnutrition in Pediatric Chronic Cholestatic Disease: An Up-to-Date Overview Maria Tessitore 1, Eduardo Sorrentino 1, Giuseppe Schiano Di Cola 1, Angelo Colucci 1, Pietro Vajro 1, Claudia Mandato 2 Abstract Published on: Aug-2021 Read more
Molecular signatures of aggressive pediatric liver cancer https://pubmed.ncbi.nlm.nih.gov/34447970/ tumours Arch Stem Cell Ther. 2021;2(1):1-4. Molecular signatures of aggressive pediatric liver cancer Michael E Johnston 1 2, Nikolai Timchenko 1 2 Abstract Published on: Aug-2021 Read more	Under-Vaccination in Pediatric Liver Transplant Candidates with Acute and Chronic Liver Disease-A Retrospective Observational Study of the European Reference Network TransplantChild https://pubmed.ncbi.nlm.nih.gov/34438566/ Liver transplant Children (Basel). 2021 Aug 3;8(8):675. doi: 10.3390/children8080675. Under-Vaccination in Pediatric Liver Transplant Candidates with Acute and Chronic Liver Disease-A Retrospective Observational Study of the European Reference Network TransplantChild Tobias Laue 1, Zeynep Demir 2, Dominique Debray 2, Mara Cananzi 3, Paola Gaio 3, Valeria Casotti 4, Lorenzo D'Antiga 4, Vaidotas Urbonas 5, Ulrich Baumann 1 Abstract Published on: Aug-2021 Read more
PEX26 gene genotype-phenotype correlation in neonates with Zellweger syndrome https://pubmed.ncbi.nlm.nih.gov/34430430/ Transl Pediatr. 2021 Jul;10(7):1825-1833. doi: 10.21037/tp-21-103. PEX26 gene genotype-phenotype correlation in neonates with Zellweger syndrome Yue He 1, Sam Bill Lin 1, Wen-Xuan Li 1, Lin Yang 2, Rong Zhang 1, Chao Chen 1, Lin Yuan 1 Abstract Background: Zellweger syndrome (ZS) is commonly manifested as facial deformities, hypotonia, and liver dysfunction. However, ZS caused by PEX26 gene mutation shows a broad and dispersed clinical pattern. In this study, the PEX26 gene in ZS was analyzed to enrich its clinical characteristics. Meanwhile, phenotypic and genotypic characteristics of Zellweger spectrum disorder (ZSD) induced by PEX26 mutation were evaluated. Published on: Aug-2021 Read more	Current Practices on Diagnosis, Prevention and Treatment of Post-Transplant Lymphoproliferative Disorder in Pediatric Patients after Solid Organ Transplantation: Results of ERN TransplantChild Healthcare Working Group Survey https://pubmed.ncbi.nlm.nih.gov/34438552/ Liver Transplant Children (Basel). 2021 Jul 29;8(8):661. doi: 10.3390/children8080661. Current Practices on Diagnosis, Prevention and Treatment of Post-Transplant Lymphoproliferative Disorder in Pediatric Patients after Solid Organ Transplantation: Results of ERN TransplantChild Healthcare Working Group Survey Published on: Aug-2021 Read more
Liver Transplantation: A Safe and Definitive Alternative to Lifelong Nitisinone for Tyrosinemia Type 1 https://pubmed.ncbi.nlm.nih.gov/34398413/ Transplant Indian J Pediatr. 2021 Aug 16. doi: 10.1007/s12098-021-03826-1. Online ahead of print. Liver Transplantation: A Safe and Definitive Alternative to Lifelong Nitisinone for Tyrosinemia Type 1 Jagadeesh Menon 1, Naresh Shanmugam 2, Joseph J Valamparampil 1, Abdul Hakeem 3, Mukul Vij 4, Anil Jalan 5, Mettu Srinivas Reddy 3, Mohamed Rela 3 6 Abstract Objectives: To report the experience of liver transplantation (LT) for tyrosinemia type 1 (TT-1). Methods: Clinical data of children with TT-1 who underwent living donor LT between July 2009 and May 2020 were retrospectively analyzed. Data included pre-LT nitisinone therapy, graft type, post-LT complications, HCC incidence, and graft/patient survival. Published on: Aug-2021 Read more	Recipient-Specific Risk Factors Impairing Patient and Graft Outcome after Pediatric Liver Transplantation-Analysis of 858 Transplantations in 38 Years https://pubmed.ncbi.nlm.nih.gov/34438532/ Liver transplant Children (Basel). 2021 Jul 27;8(8):641. doi: 10.3390/children8080641. Recipient-Specific Risk Factors Impairing Patient and Graft Outcome after Pediatric Liver Transplantation-Analysis of 858 Transplantations in 38 Years Christoph Leiskau 1 2, Norman Junge 1, Eva-Doreen Pfister 1, Imeke Goldschmidt 1, Frauke Mutschler 1, Tobias Laue 1, Johanna Ohlendorf 1, Hamoud Nasser 1, Jan Beneke 3, Nicolas Richter 4, Florian Vondran 4, Ulrich Baumann 1 Abstract Published on: Aug-2021 Read more

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