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A Case Series on Genotype and Outcome of Liver Transplantation in Children with Niemann-Pick Disease Type C https://pubmed.ncbi.nlm.nih.gov/34572251/ Neimann Pick Children (Basel). 2021 Sep 17;8(9):819. doi: 10.3390/children8090819. A Case Series on Genotype and Outcome of Liver Transplantation in Children with Niemann-Pick Disease Type C Line Modin 1 2, Vicky Ng 3, Paul Gissen 4, Julian Raiman 3, Eva Doreen Pfister 5, Anibh Das 5, René Santer 6, Hanna Faghfoury 3, Saikat Santra 2, Ulrich Baumann 7 Abstract Background: To report on clinical presentation and outcomes of children who underwent liver transplantation (LTx) and were subsequently diagnosed to have Niemann-Pick type C (NPC). Methods: Retrospective, descriptive, multi-centre review of children diagnosed with NPC who underwent LTx (2003-2018). Diagnosis was made by filipin skin test or genetic testing. Published on: Sep-2021 Read more	The significance of isolated aspartate aminotransferase (AST) elevation in healthy pediatric patients https://pubmed.ncbi.nlm.nih.gov/34564873/ Acta Paediatr. 2021 Sep 26. doi: 10.1111/apa.16123. Online ahead of print. The significance of isolated aspartate aminotransferase (AST) elevation in healthy pediatric patients Ramit Magen-Rimon 1, Galit Tal 2 3, Marielle Kaplan 4, Ron Shaoul 1 Abstract Aim: Aspartate aminotransferase (AST) is an enzyme expressed in several organs, therefore, AST elevation may reflect outside of liver pathology. AST elevation may also be associated with macro AST (m-AST). The aim of this study was to evaluate the long term course of children with prolonged isolated AST elevation and the prevalence of m-AST in our cohort. Published on: Sep-2021 Read more
ABO Incompatible Liver Transplantation in Children: A 20 Year Experience from Centres in the TransplantChild European Reference Network https://pubmed.ncbi.nlm.nih.gov/34572193/ Liver transplant Children (Basel). 2021 Aug 31;8(9):760. doi: 10.3390/children8090760. ABO Incompatible Liver Transplantation in Children: A 20 Year Experience from Centres in the TransplantChild European Reference Network Małgorzata Markiewicz-Kijewska 1, Piotr Kaliciński 1, Juan Torres Canizales 2, Angelo Di Giorgio 3, Ulrich Baumann 4, Carl Jorns 5, Alastair Baker 6, Maria Francelina Lopes 7, Esteban Frauca Remacha 8, Eduardo Lopez-Granados 2, Paloma Jara Vega 8, Maria-Sole Basso 9, Grzegorz Kowalewski 1, Diana Kamińska 10, Sandra Ferreira 11, Daniela Liccardo 9, Andrea Pietrobattista 9, Marco Spada 12, On Behalf Of Ern TransplantChild Healthcare Working Group Abstract Published on: Sep-2021 Read more	The significance of isolated aspartate aminotransferase (AST) elevation in healthy pediatric patients https://pubmed.ncbi.nlm.nih.gov/34564873/ Acta Paediatr. 2021 Sep 26. doi: 10.1111/apa.16123. Online ahead of print. The significance of isolated aspartate aminotransferase (AST) elevation in healthy pediatric patients Ramit Magen-Rimon 1, Galit Tal 2 3, Marielle Kaplan 4, Ron Shaoul 1 Abstract Aim: Aspartate aminotransferase (AST) is an enzyme expressed in several organs, therefore, AST elevation may reflect outside of liver pathology. AST elevation may also be associated with macro AST (m-AST). The aim of this study was to evaluate the long term course of children with prolonged isolated AST elevation and the prevalence of m-AST in our cohort. Published on: Sep-2021 Read more
Intrahepatic cholangiocyte regeneration from an Fgf-dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome https://pubmed.ncbi.nlm.nih.gov/34569629/ Alagille syndrome Hepatology. 2021 Sep 27. doi: 10.1002/hep.32173. Online ahead of print. Intrahepatic cholangiocyte regeneration from an Fgf-dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome Chengjian Zhao 1 2, Joseph J Lancman 1, Yi Yang 2, Keith P Gates 1, Dan Cao 2, Lindsey Barske 3, Jonathan Matalonga 1, Xiangyu Pan 2, Jiaye He 4, Alyssa Graves 4, Jan Huisken 4 5, Chong Chen 2, P Duc Si Dong 1 6 Abstract Published on: Sep-2021 Read more	Liver stiffness measurement as a quantitative method for liver fibrosis in children with non-alcoholic fatty liver disease: A meta-analysis https://pubmed.ncbi.nlm.nih.gov/34554611/ NAFLD J Paediatr Child Health. 2021 Sep 23. doi: 10.1111/jpc.15751. Online ahead of print. Liver stiffness measurement as a quantitative method for liver fibrosis in children with non-alcoholic fatty liver disease: A meta-analysis Bingtian Dong 1, Yuping Chen 2, Guorong Lyu 1 3, Ran Qin 4 Abstract Aim: This study assessed the diagnostic performance of liver stiffness measurement (LSM) in detecting liver fibrosis in paediatric patients with non-alcoholic fatty liver disease (NAFLD) through meta-analysis. Published on: Sep-2021 Read more
Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions https://pubmed.ncbi.nlm.nih.gov/34568760/ Liver transplant Review SN Compr Clin Med. 2021 Sep 21;1-7. doi: 10.1007/s42399-021-01050-8.Online ahead of print. Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions Amr Alnagar 1 2, Nicola Ruth 3 4, Mohamed Elsharif 1, Kejd Bici 5, Ahmed Shawky 2, Deirdre Kelly 5 4, Magdy Attia 1 Abstract Published on: Sep-2021 Read more	Liver Abscesses as a Sign of Chronic Granulomatous Disease in Adolescent https://pubmed.ncbi.nlm.nih.gov/34589361/ Liver abscess Case Reports Cureus. 2021 Aug 26;13(8):e17467. doi: 10.7759/cureus.17467.eCollection 2021 Aug. Liver Abscesses as a Sign of Chronic Granulomatous Disease in Adolescent Hussain A Al Ghadeer 1, Fadi N Busaleh 1, Jaber A Al Habeeb 2, Rabab M Alaithan 1, Abdullah E Almutahhar 1, Murtadha M Bin Abd 1, Mishael M Aldawood 1 Abstract Published on: Sep-2021 Read more
Disease-Associated Gut Microbiota Reduces the Profile of Secondary Bile Acids in Pediatric Nonalcoholic Fatty Liver Disease https://pubmed.ncbi.nlm.nih.gov/34568090/ NAFLD Front Cell Infect Microbiol. 2021 Sep 9;11:698852. doi: 10.3389/fcimb.2021.698852.eCollection 2021. Disease-Associated Gut Microbiota Reduces the Profile of Secondary Bile Acids in Pediatric Nonalcoholic Fatty Liver Disease Jiake Yu 1, Hu Zhang 1, Liya Chen 1, Yufei Ruan 1, Yiping Chen 1, Qi Liu 1 Abstract Published on: Sep-2021 Read more	Predictors of patient and graft survival following pediatric liver transplantation: Long-term analysis of more than 300 cases from single centre https://pubmed.ncbi.nlm.nih.gov/34545678/ Transplant Pediatr Transplant. 2021 Sep 20;e14139. doi: 10.1111/petr.14139. Online ahead of print. Predictors of patient and graft survival following pediatric liver transplantation: Long-term analysis of more than 300 cases from single centre Amr Alnagar 1 2, Khaled Daradka 1 3, Eirini Kyrana 1, Marumbo Mtegha 1, Karthikeyan Palaniswamy 1, Sanjay Rajwal 1, Jamila Mulla 1, Moira O'meara 1, Mohamed Karam 2, Ahmed Shawky 2, Abdul Rahman Hakeem 1, Vivek Upasani 1, Vijayanand Dhakshinamoorthy 1, Raj Prasad 1, Magdy Attia 1 Abstract Published on: Sep-2021 Read more

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