Event Videos

https://pubmed.ncbi.nlm.nih.gov/32585237/ liver transplant
J Pediatr. 2020 Jun 22;S0022-3476(20)30756-3.
doi: 10.1016/j.jpeds.2020.06.053.Online ahead of print.

Decreased Incidence of Hepatic Artery Thrombosis in Pediatric Liver Transplantation Utilizing Technical Variant Grafts: Report of the Society of Pediatric Liver Transplantation (SPLIT) Experience

Noelle H Ebel 1, Evelyn K Hsu 2, André A S Dick 3, Michele L Shaffer 4, Kristen Carlin 5, Simon P Horslen 2
PMID: 32585237
DOI: 10.1016/j.jpeds.2020.06.053

Abstract

Objective: To evaluate risk factors for hepatic artery thrombosis (HAT) and examine the long-term outcomes of graft and patient survival following HAT in pediatric recipients of liver transplantation.

Published on: 
Jun-2020

https://pubmed.ncbi.nlm.nih.gov/32498678/ Biliary atresia

BMC Pediatr. 2020 Jun 4;20(1):276.
doi: 10.1186/s12887-020-02172-z.

Combination of Gamma-Glutamyl Transferase and Liver Stiffness Measurement for Biliary Atresia Screening at Different Ages: A Retrospective Analysis of 282 Infants

Qiulong Shen 1, Sarah Siyin Tan 1, Zengmeng Wang 1, Siyu Cai 2, Wenbo Pang 1, Chunhui Peng 1, Yajun Chen 3
PMID: 32498678

PMCID: PMC7271542

DOI: 10.1186/s12887-020-02172-z

Abstract

Background: This study aims to explore the diagnostic accuracy of the combination of gamma-glutamyl transferase (GGT) and liver stiffness measurement (LSM) for biliary atresia (BA) screening at different ages.

Published on: 
Jun-2020

https://pubmed.ncbi.nlm.nih.gov/32553668/ biliary atresia

J Hepatol. 2020 Jun 16;S0168-8278(20)30383-4.
doi: 10.1016/j.jhep.2020.06.012.Online ahead of print.

Beta-amyloid Deposition Around Hepatic Bile Ducts Is a Novel Pathobiological and Diagnostic Feature of Biliary Atresia

Rosana Ottakandathil Babu 1, Vincent Chi Hang Lui 2, Yan Chen 3, Rachel Sze Wan Yiu 1, Yongqin Ye 4, Ben Niu 5, Zhongluan Wu 6, Ruizhong Zhang 3, Michelle On Na Yu 7, Patrick Ho Yu Chung 8, Kenneth Kak Yuen Wong 8, Huimin Xia 3, Michael Qi Zhang 9, Bin Wang 10, Urban Lendahl 11, Paul Kwong Hang Tam 12
PMID: 32553668

DOI: 10.1016/j.jhep.2020.06.012

Abstract

Published on: 
Jun-2020

https://pubmed.ncbi.nlm.nih.gov/32506543/ Hepatitis
Acta Paediatr. 2020 Jun 7.
doi: 10.1111/apa.15403. Online ahead of print.
Paediatric Hepatitis B and Hepatitis C Virus Infections: An Observational Study of a Danish Cohort
Christoph Norden 1, Mikkel Malham 1, Sannie Nordly 1, Dorthe Grosen 2, Helene Kvistgaard 3, Mette S Kjaer 4, Vibeke Brix Christensen 5

PMID: 32506543

DOI: 10.1111/apa.15403

Abstract

Aim: The aim of this study was to describe the epidemiological and clinical characteristics in children with either chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection in Denmark.

Published on: 
Jun-2020

https://pubmed.ncbi.nlm.nih.gov/32464706/

Hepatology. 2020 May 28.
doi: 10.1002/hep.31393. Online ahead of print.
The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children

Abstract

Background & aims: Disease progression in children with primary sclerosing cholangitis (PSC) is variable. Prognostic and risk-stratification tools exist for adult-onset PSC, but not for children. We aimed to create a tool that accounts for the biochemical and phenotypic features and early disease stage of pediatric PSC.

Published on: 
Jun-2020

https://pubmed.ncbi.nlm.nih.gov/32492754/ PFIC
Liver Int. 2020 Jun 3.

Potential of Ileal Bile Acid Transporter Inhibition as a Therapeutic Target in Alagille Syndrome and Progressive Familial Intrahepatic Cholestasis
Binita M Kamath 1 2, Philip Stein 3, Roderick H J Houwen 4, Henkjan J Verkade 5
PMID: 32492754

DOI: 10.1111/liv.14553

Abstract

Published on: 
Jun-2020

https://pubmed.ncbi.nlm.nih.gov/32381466/?from_term=children+AND+liver&f... NAFLD

J Pediatr.2020 May 4;S0022-3476(20)30392-9.
doi: 10.1016/j.jpeds.2020.03.038.Online ahead of print.

Glomerular Hyperfiltration Is Associated With Liver Disease Severity in Children With Nonalcoholic Fatty Liver Disease
Toshifumi Yodoshi 1, Ana Catalina Arce-Clachar 2, Qin Sun 3, Lin Fei 4, Kristin Bramlage 1, Stavra A Xanthakos 2, Francisco Flores 5, Marialena Mouzaki 6

Abstract

Objectives: To determine the prevalence of renal impairment in a large cohort of youths with histologically confirmed nonalcoholic fatty liver disease (NAFLD), and to determine its association with liver disease severity.

Published on: 
May-2020

https://pubmed.ncbi.nlm.nih.gov/32585038/
Acta Paediatr. 2020 Jun 25.
doi: 10.1111/apa.15446. Online ahead of print.
Prolonged Abnormal Isolated Aminotransferase Levels in Healthy Children Is a Benign Condition
Ramit Magen-Rimon 1, Ron Shaoul 1

PMID: 32585038

DOI: 10.1111/apa.15446

Abstract

Aim: Hypertransaminasemia is common incidental finding in children. It has been demonstrated that even prolonged elevation usually resolves spontaneously without clear etiology. The aim of this study was to evaluate whether a longer follow up period, on a larger group, supports the previous findings.

Methods: We retrospectively reviewed medical charts of children diagnosed with prolonged idiopathic hypertransaminasemia, which spontaneously resolved over the follow-up period.

Published on: 
Jun-2020

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