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Clinically Evident Portal Hypertension: An Operational Research Definition for Future Investigations in the Pediatric Population

https://www.ncbi.nlm.nih.gov/pubmed/30908382 Portal Hypertension
J Pediatr Gastroenterol Nutr. 2019 Mar 18. doi: 10.1097/MPG.0000000000002333. [Epub ahead of print]
Clinically Evident Portal Hypertension: An Operational Research Definition for Future Investigations in the Pediatric Population.
Bass LM1, Shneider BL2, Henn L3, Goodrich NP3, Magee JC4; Childhood Liver Disease Research Network (ChiLDReN).

Abstract

Published on:

Mar-2019

Treatment of Chronic Hepatitis C Infection with Direct Acting Antivirals in Adolescents with Thalassemia Major.

https://www.ncbi.nlm.nih.gov/pubmed/?term=30097845 Hepatitis C
Indian J Pediatr. 2019 Feb;86(2):148-153. doi: 10.1007/s12098-018-2752-7. Epub 2018 Aug 10.
Treatment of Chronic Hepatitis C Infection with Direct Acting Antivirals in Adolescents with Thalassemia Major.
Nagral A1,2,3, Jhaveri A4, Sawant S5, Parikh NS4, Nagral N6, Merchant R7, Gandhi M8,9,10.
Author information

Abstract

OBJECTIVES:
To assess the efficacy and safety of sofosbuvir based generic Direct Acting Antivirals (DAAs) in treatment of Hepatitis C virus (HCV) in adolescents with thalassemia major (TM).

METHODS:

Published on:

Feb-2019

Passenger Lymphocyte Syndrome after Pediatric Liver Transplantation

https://www.ncbi.nlm.nih.gov/pubmed/30889120 Liver transplant

J Pediatr Gastroenterol Nutr. 2019 Mar 15. doi: 10.1097/MPG.0000000000002337. [Epub ahead of print]
Passenger Lymphocyte Syndrome after Pediatric Liver Transplantation.
Woolfson JP, Vandriel SM, Stephens D, Dharmaraj BG, De Angelis M, Cattral MS, Ghanekar A, Grant DR, Avitzur Y, Ng VL.

Abstract

BACKGROUND:

Passenger lymphocyte syndrome (PLS) is a less known etiology of acute onset anemia following ABO-compatible (ABO-c) liver transplantation (LT). Available literature on PLS following pediatric LT is limited. Therefore, we evaluated the prevalence, clinical course and risk factors of PLS in children following ABO-c LT.

METHODS:

Published on:

Mar-2019

Early post-operative intravenous tacrolimus in pediatric liver transplant recipients is not superior to oral tacrolimus.

https://www.ncbi.nlm.nih.gov/pubmed/30719833 liver transplant
Pediatr Transplant. 2019 Feb 4:e13368. doi: 10.1111/petr.13368. [Epub ahead of print]
Early post-operative intravenous tacrolimus in pediatric liver transplant recipients is not superior to oral tacrolimus.
Sabra TA1,2,3, Okajima H1, Yoshizawa A1, Ogawa E1, Okamoto S1, Osman MA2, Saad-Eldin Y4, Uemoto S1.
Author information

Abstract

Published on:

Feb-2019

AARC-ACLF score: best predictor of outcome in children and adolescents with decompensated Wilson disease

https://www.ncbi.nlm.nih.gov/pubmed/30888628 Wilson disease
Hepatol Int. 2019 Mar 19. doi: 10.1007/s12072-019-09938-3. [Epub ahead of print]
AARC-ACLF score: best predictor of outcome in children and adolescents with decompensated Wilson disease.

Alam S1, Lal BB2, Sood V2, Khanna R2, Kumar G3.

Abstract

BACKGROUND AND AIMS:
Doubts have been raised about efficacy of New Wilson's index (NWI) in predicting LiverTransplant (LT) or mortality in decompensated Wilson Disease (WD) patients. APASL ACLF Research Consortium (AARC) has introduced a new score (AARC-ACLF) which has not been studied in children.

METHODS:

Published on:

Mar-2019

Steroid Free Treatment of Autoimmune Hepatitis in Selected Children

https://www.ncbi.nlm.nih.gov/pubmed/30723013 Autoimmune hepatitis
J Pediatr. 2019 Feb 2. pii: S0022-3476(19)30022-8. doi: 10.1016/j.jpeds.2018.12.070. [Epub ahead of print]

Steroid Free Treatment of Autoimmune Hepatitis in Selected Children.
Wehrman A1, Waisbourd-Zinman O2, Shah A1, Hilmara D3, Lin H1, Rand EB4.
Author information

Abstract
Current guidelines recommend steroids for induction of remission in all children diagnosed with autoimmune hepatitis regardless of the clinical presentation. In this report, we describe our experience in treating selected asymptomatic children with autoimmune hepatitis using a steroid-free regimen; this treatment strategy was safe and effective in inducing remission.

Published on:

Feb-2019

Novel insights into the assessment of risk of upper gastrointestinal bleeding in decompensated cirrhotic children

https://www.ncbi.nlm.nih.gov/pubmed/30888111 Cirrhosis
Pediatr Transplant. 2019 Mar 19:e13390. doi: 10.1111/petr.13390. [Epub ahead of print]
Novel insights into the assessment of risk of upper gastrointestinal bleeding in decompensated cirrhotic children.
Bonnet N1, Paul J2, Helleputte T2, Veyckemans F3, Pirotte T4, Prégardien C4, Eeckhoudt S5, Hermans C6, Detaille T7, Clapuyt P8, Menten R8, Dumitriu D8, Reding R9, Scheers I1, Varma S1, Smets F1, Sokal E1, Stéphenne X1.

Abstract

OBJECTIVES:

Published on:

Mar-2019

Amoebic liver abscess: Outcomes of percutaneous needle aspiration vs drain placement in paediatric population.

https://www.ncbi.nlm.nih.gov/pubmed/30736649 Amoebic liver abscess
J Pak Med Assoc. 2019 Feb;69(Suppl 1)(1):S29-S32.
Amoebic liver abscess: Outcomes of percutaneous needle aspiration vs drain placement in paediatric population.
Salim A1, Jeelani SM1, Qazi SH2, Mirza W3.
Author information

Abstract

OBJECTIVE:
To compare the effectiveness of percutaneous catheter drain placement with percutaneous needle aspiration in terms of hospital stay, time to resolution of symptoms and cost of intervention performed.

METHODS:

Published on:

Feb-2019

Wilson’s Disease patients pay fraction of earlier cost of drug

Source: TOI, 17 March 2019
Link to Epaper: https://epaper.timesgroup.com/Olive/ODN/TimesOfIndia/get/image.ashx?kind...

https://timesofindia.indiatimes.com/city/mumbai/hearing-patients-plight-...

Attachment	Size
toi_wilson_drug_cheap.png	723.58 KB

Cost Effectiveness of Early Treatment with Direct-Acting Antiviral Therapy in Adolescent Patients with Hepatitis C Virus Infection.

https://www.ncbi.nlm.nih.gov/pubmed/30738661 Hepatitis C
J Pediatr. 2019 Feb 6. pii: S0022-3476(18)31729-3. doi: 10.1016/j.jpeds.2018.12.012. [Epub ahead of print]
Cost Effectiveness of Early Treatment with Direct-Acting Antiviral Therapy in Adolescent Patients with Hepatitis C Virus Infection.
Nguyen J1, Barritt Iv AS2, Jhaveri R3.
Author information

Abstract

OBJECTIVE:

To evaluate the cost effectiveness of early treatment with direct-acting antiviral therapy in adolescent patients with chronic hepatitis C virus (HCV) infection compared with treatment deferral.

STUDY DESIGN:

Published on:

Feb-2019

Success Stories

Event Videos

Clinically Evident Portal Hypertension: An Operational Research Definition for Future Investigations in the Pediatric Population

Treatment of Chronic Hepatitis C Infection with Direct Acting Antivirals in Adolescents with Thalassemia Major.

Passenger Lymphocyte Syndrome after Pediatric Liver Transplantation

Early post-operative intravenous tacrolimus in pediatric liver transplant recipients is not superior to oral tacrolimus.

AARC-ACLF score: best predictor of outcome in children and adolescents with decompensated Wilson disease

Steroid Free Treatment of Autoimmune Hepatitis in Selected Children

Novel insights into the assessment of risk of upper gastrointestinal bleeding in decompensated cirrhotic children

Amoebic liver abscess: Outcomes of percutaneous needle aspiration vs drain placement in paediatric population.

Wilson’s Disease patients pay fraction of earlier cost of drug

Cost Effectiveness of Early Treatment with Direct-Acting Antiviral Therapy in Adolescent Patients with Hepatitis C Virus Infection.

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