Event Videos

http://www.ncbi.nlm.nih.gov/pubmed/26485605

Kolachala VL, Jiang R, Abramowsky CR, Gupta NA. Contrast-Based Real-Time Assessment of Microcirculatory Changes in a Fatty Liver after Ischemia Reperfusion Injury. J Pediatric Gastroenterology Nutr. 2016 Mar; 62(3): 429-36.

Abstract

OBJECTIVES:
A fatty liver is known to have impairment of microcirculation, which is worsened after ischemia reperfusion injury (IRI). This makes most fatty grafts unsuitable for transplantation, and in the absence of real time assessment of microcirculation this selection has been at best, random. The aim of this study was to demonstrate the utility of a contrast enhanced ultrasound model in quantitative assessment of the microcirculation of a fatty liver.

METHODS:

Published on: 
Mar-2016

http://www.ncbi.nlm.nih.gov/pubmed/26381818

Lv Y, He C, Guo W, Yin Z, Wang J, Zhang B, Meng X, Cai J, Luo B, Wu F, Niu J, Fan D, Han G. Transjugular Intrahepatic Portosystemic Shunt for Extrahepatic Portal Venous Obstruction in Children. J Pediatr Gastroenterol Nutr. 2016
Feb;62(2):233-41.

Abstract

OBJECTIVES:
To evaluate the feasibility and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) for extrahepatic portal venous obstruction with recurrent variceal bleeding in children.

METHODS:

Published on: 
Feb-2016

http://www.ncbi.nlm.nih.gov/pubmed/26409215

Murillo O, Luqui DM, Gazquez C, Martinez-Espartosa D, Navarro-Blasco I, Monreal JI, Guembe L, Moreno-Cermeño A, Corrales FJ, Prieto J, Hernandez-Alcoceba R, Gonzalez-Aseguinolaza G. Long-term metabolic correction of Wilson's disease in a murine model by gene therapy. J Hepatol. 2016 Feb; 64(2):419-26.

Abstract

BACKGROUND & AIMS:
Wilson's disease (WD) is an autosomal recessively inherited copper storage disorder due to mutations in the ATP7B gene that causes hepatic and neurologic symptoms. Current treatments are based on lifelong copper chelating drugs and zinc salts, which may cause side effects and do not restore normal copper metabolism. In this work we assessed the efficacy of gene therapy to treat this condition.

METHODS:

Published on: 
Feb-2016

http://www.ncbi.nlm.nih.gov/pubmed/26340411

. Cirrhosis
De Pietri L, Bianchini M, Montalti R, De Maria N, Di Maira T, Begliomini B, Gerunda GE, di Benedetto F, Garcia-Tsao G, Villa E. Thrombelastography-guided blood product use before invasive procedures in cirrhosis with severe coagulopathy: A randomized, controlled trial. Hepatology. 2016 Feb; 63(2):566-73.

Abstract

Published on: 
Feb-2016

http://www.ncbi.nlm.nih.gov/pubmed/26223345
Hepatitis B
Jonas MM, Chang MH, Sokal E, Schwarz KB, Kelly D, Kim KM, Ling SC, Rosenthal P, Oraseanu D, Reynolds L, Thiry A, Ackerman P. Randomized, controlled trial of entecavir versus placebo in children with hepatitis B envelope antigen-positive chronic hepatitis B. Hepatology. 2016 Feb; 63(2):377-87.

Abstract

Published on: 
Feb-2016

http://www.ncbi.nlm.nih.gov/pubmed/26840667

. Galactosemia

Sarma MS, Srivastava A, Yachha SK, Poddar U, Mathias A. Classical Galactosemia Among Indian Children: Presentation and Outcome from a Pediatric Gastroenterology Center. Indian Pediatr. 2016 Jan 8; 53(1):27-31.

Abstract

OBJECTIVE:
To analyze the presentation and predictors of outcome of children with galactosemia.

METHODS:
Analysis of clinical, laboratory, microbiological profile and outcome of patients fulfilling the diagnostic criteria: i) clinical setting; ii) reduced erythrocyte Gal-1-PUT enzyme activity; and iii) unequivocal response to lactose-free diet.

RESULTS:

Published on: 
Jan-2016

http://www.ncbi.nlm.nih.gov/pubmed/26284540

Alagille’s syndrome

Alhammad A, Kamath BM, Chami R, Ng VL, Chavhan GB. Solitary Hepatic Nodule Adjacent to the Right Portal Vein: A Common Finding of Alagille Syndrome? J Pediatr Gastroenterol Nutr. 2016 Feb; 62(2):226-32.

Abstract

BACKGROUND:
Hepatic lesions have been described in Alagille syndrome (ALGS) in isolated case reports, and most of these have been reported to be hepatocellular carcinoma.

OBJECTIVES:
The aim of the present study was to determine the frequency, imaging, and histopathologic characteristics of hepatic lesions in children with ALGS.

METHODS:

Published on: 
Feb-2016

http://www.ncbi.nlm.nih.gov/pubmed/26513612

Cengiz M, Ozenirler S, Kocabiyik M. Serum β-trophin level as a new marker for noninvasive assessment of nonalcoholic fatty liver disease and liver fibrosis. Eur J Gastroenterol Hepatol. 2016 Jan; 28(1):57-63.

Abstract

OBJECTIVE:
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease and evaluation of fibrosis is important. We aimed to investigate the utility of serum β-trophin in NAFLD and its ability to predict liver fibrosis.

PATIENTS AND METHODS:

Published on: 
Jan-2016

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