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Prospective evaluation of the diagnostic accuracy of hepatic copper content, as determined using the entire core of a liver biopsy sample http://www.ncbi.nlm.nih.gov/pubmed/26095812 . Wilson's Disease Yang X, Tang XP, Zhang YH, Luo KZ, Jiang YF, Luo HY, Lei JH, Wang WL, Li MM, Chen HC, Deng SL, Lai LY, Liang J, Zhang M, Tian Y, Xu Y. Prospective evaluation of the diagnostic accuracy of hepatic copper content, as determined using the entire core of a liver biopsy sample. Hepatology. 2015 Dec;62(6):1731-41. Abstract Published on: Dec-2015 Read more	Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study http://www.ncbi.nlm.nih.gov/pubmed/26226452 Cirrhosis Plompen EP, Darwish Murad S, Hansen BE, Loth DW, Schouten JN, Taimr P, Hofman A, Uitterlinden AG, Stricker BH, Janssen HL, Leebeek FW. Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study. J Hepatol. 2015 Dec; 63(6):1459-65. Abstract BACKGROUND & AIMS: The coagulation system is known to be involved in fibrogenesis in patients with liver disease. We investigated whether common genetic prothrombotic risk factors are associated with an increased risk of fibrosis in the general population. METHODS: Published on: Dec-2015 Read more
Chronic hepatitis C virus infection is associated with increased risk of preterm birth: a meta-analysis of observational studies http://www.ncbi.nlm.nih.gov/pubmed/26081198 Hepatitis C Huang QT, Huang Q, Zhong M, Wei SS, Luo W, Li F, Yu YH. Chronic hepatitis C virus infection is associated with increased risk of preterm birth: a meta-analysis of observational studies. J Viral Hepat. 2015 Dec; 22(12):1033-42. Abstract Published on: Dec-2015 Read more	Prognostic impact of surgery and radiofrequency ablation on single nodular HCC ⩽5 cm: Cohort study based on serum HCC markers http://www.ncbi.nlm.nih.gov/pubmed/26212030 Hepatocellular Carcinoma Ueno M, Hayami S, Shigekawa Y, Kawai M, Hirono S, Okada K, Tamai H, Shingaki N, Mori Y, Ichinose M, Yamaue H. Prognostic impact of surgery and radiofrequency ablation on single nodular HCC ⩽5 cm: Cohort study based on serum HCC markers. J Hepatol. 2015 Dec;63(6):1352-9. Abstract BACKGROUND & AIMS: Published on: Dec-2015 Read more
Antiviral therapy in chronic hepatitis E: a systematic review http://www.ncbi.nlm.nih.gov/pubmed/25760481 Hepatitis E Peters van Ton AM, Gevers TJ, Drenth JP. Antiviral therapy in chronic hepatitis E: a systematic review. J Viral Hepat. 2015 Dec; 22(12):965-73. Abstract Hepatitis E viral infection can lead to a chronic infection in immunocompromised patients, resulting in progressive liver disease and cirrhosis. Isolated cases have shown that treatment with ribavirin or pegylated interferon-α can result in viral eradication. This systematic review evaluated efficacy and safety of both treatments in chronic hepatitis E. A systematic literature search was performed on PubMed, Web of Science and clinicaltrials.gov for articles and abstracts. Published on: Dec-2015 Read more	Zinc Therapy for Wilson Disease in Children in French Pediatric Centers http://www.ncbi.nlm.nih.gov/pubmed/26230903 Santiago R, Gottrand F, Debray D, Bridoux L, Lachaux A, Morali A, Lapeyre D, Lamireau T. Zinc Therapy for Wilson Disease in Children in French Pediatric Centers. J Pediatr Gastroenterol Nutr. 2015 Dec;61(6):613-8. Abstract BACKGROUND AND AIMS: Zinc therapy is considered a good option in Wilson disease (WD), as a first-line treatment in presymptomatic children and a maintenance therapy after the initial chelator therapy. The aim of the study was to determine the practical use of zinc treatment in French pediatric centers. METHODS: A national survey was conducted in the 6 French centers using zinc acetate to treat WD. Clinical and biological parameters, dosage, and outcome were recorded. RESULTS: Published on: Dec-2015 Read more
Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy http://www.ncbi.nlm.nih.gov/pubmed/26261009 Lammers WJ, Hirschfield GM, Corpechot C, Nevens F, Lindor KD, Janssen HL, Floreani A, Ponsioen CY, Mayo MJ, Invernizzi P, Battezzati PM, Parés A, Burroughs AK, Mason AL, Kowdley KV, Kumagi T, Harms MH, Trivedi PJ, Poupon R, Cheung A, Lleo A, Caballeria L, Hansen BE, van Buuren HR; Global PBC Study Group. Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy. Gastroenterology. 2015 Dec; 149(7):1804-1812. Abstract BACKGROUND & AIMS: Published on: Dec-2015 Read more	Hepato-cellular nodules expressing markers of hepatocellular adenomas in Budd-Chiari syndrome and other rare hepatic vascular disorders http://www.ncbi.nlm.nih.gov/pubmed/26119687 Budd chiari syndrome Sempoux C, Paradis V, Komuta M, Wee A, Calderaro J, Balabaud C, Quaglia A, Bioulac-Sage P. Hepato-cellular nodules expressing markers of hepatocellular adenomas in Budd-Chiari syndrome and other rare hepatic vascular disorders. J Hepatol. 2015 Nov; 63(5):1173-80. Abstract BACKGROUND & AIMS: A broad range of hepatocellular nodules has been reported in hepatic vascular disorders. It is not clear whether hepatocellular adenoma (HCA) in this context share the same characteristics as conventional HCA. The aim of this study was to carry out a retrospective multicenter survey of hepatocellular nodules associated with hepatic vascular disorders. METHODS: Published on: Nov-2015 Read more
EASL Clinical Practice Guidelines: Autoimmune hepatitis http://www.ncbi.nlm.nih.gov/pubmed/26341719 Autoimmune Hepatitis European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Autoimmune hepatitis. J Hepatol. 2015 Oct; 63(4):971-1004. Published on: Dec-2015	Safety, complications and outcome of large volume paracentesis with or without albumin therapy in children with severe ascites due to liver disease http://www.ncbi.nlm.nih.gov/pubmed/26134185 ascites Sen Sarma M, Yachha SK, Bhatia V, Srivastava A, Poddar U. Safety, complications and outcome of large volume paracentesis with or without albumin therapy in children with severe ascites due to liver disease. J Hepatol. 2015 Nov; 63(5):1126-32. Abstract BACKGROUND & AIMS: There are currently no published data on post-paracentesis circulatory dysfunction (PPCD) or its prevention in children. Our study was aimed to analyze the safety and complications of large volume paracentesis (LVP) in children with severe ascites due to chronic liver disease with or without albumin therapy. METHODS: Published on: Nov-2015 Read more

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