Event Videos

http://www.ncbi.nlm.nih.gov/pubmed/26147631

Indolfi G, Bartolini E, Serranti D, Azzari C, Resti M. Hepatitis C in Children Co-infected With Human Immunodeficiency Virus. J Pediatr Gastroenterol Nutr. 2015 Oct; 61(4):393-9.

Abstract

OBJECTIVES:
The objective of this systematic review was to summarize evidence regarding hepatitis C in hepatitis C virus/human immunodeficiency virus (HCV/HIV)-co-infected children focusing on mother-to-child transmission, clinical and laboratory features, outcome, and therapies.

METHODS:
A literature search was performed using multiple keywords and standardized terminology in MEDLINE, EMBASE, and Cochrane databases dating back to their inception up to April 1, 2015, using the following terms hepatitis C virus, HIV, and child.

RESULTS:

Published on: 
Oct-2015

http://www.ncbi.nlm.nih.gov/pubmed/26049709
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Aquarius M, Smeets FG, Konijn HW, Stassen PM, Keulen ET, Van Deursen CT, Masclee AA, Keulemans YC. Prospective multicenter validation of the Glasgow Blatchford bleeding score in the management of patients with upper gastrointestinal hemorrhage presenting at an emergency department. Eur J Gastroenterol Hepatol. 2015 Sep;27(9):1011-6.

Abstract

BACKGROUND/AIMS:
The Glasgow Blatchford Bleeding Score (GBS) has been developed to assess the need for treatment in patients with acute upper gastrointestinal hemorrhage (UGIH) presenting at emergency departments (EDs). We aimed (a) to determine the validity of the GBS and Rockall scoring systems for prediction of need for treatment and (b) to identify the optimal cut-off value of the GBS.

Published on: 
Sep-2015

http://www.ncbi.nlm.nih.gov/pubmed/25516418

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Jauregui-Amezaga A, Rimola J, Ordás I, Rodríguez S, Ramírez-Morros A, Gallego M, Masamunt MC, Llach J, González-Suárez B, Ricart E, Panés J. Value of endoscopy and MRI for predicting intestinal surgery in patients with Crohn's disease in the era of biologics. Gut. 2015 Sep; 64(9):1397-402.

Abstract

OBJECTIVE:
Severe endoscopic lesions (SEL) in patients with colonic Crohn's disease (CD) have been linked to higher risk of colectomy. The aims of this study were to reassess the predictive value of colonoscopy compared against MRI for requirement of resection surgery in patients with CD and determine the influence of current therapeutic options.

DESIGN:

Published on: 
Sep-2015

http://www.ncbi.nlm.nih.gov/pubmed/26020376

Cirrhosis, EHPVO

Colecchia A, Marasco G, Taddia M, Montrone L, Eusebi LH, Mandolesi D, Schiumerini R, Di Biase AR, Festi D. Liver and spleen stiffness and other noninvasive methods to assess portal hypertension in cirrhotic patients: a review of the literature. Eur J Gastroenterol Hepatol. 2015 Sep; 27(9):992-1001.

Abstract

Published on: 
Sep-2015

http://www.ncbi.nlm.nih.gov/pubmed/25641421
. Telbivudine

Han GR, Jiang HX, Yue X, Ding Y, Wang CM, Wang GJ, Yang YF. Efficacy and safety of telbivudine treatment: an open-label, prospective study in pregnant women for the prevention of perinatal transmission of hepatitis B virus infection. J Viral Hepat. 2015 Sep; 22(9):754-62.

Abstract

Published on: 
Sep-2015

http://www.ncbi.nlm.nih.gov/pubmed/25885880

Ecochard-Dugelay E, Lambert V, Schleich JM, Duché M, Jacquemin E, Bernard O. Portopulmonary Hypertension in Liver Disease Presenting in Childhood. J Pediatr Gastroenterol Nutr. 2015 Sep; 61(3):346-54.

Abstract

OBJECTIVE:
Portopulmonary hypertension (POPH) is a known complication of cirrhosis in adults, but there is little information on its incidence and outcome in children with liver disease. We report 14 patients with POPH and present a synthesis of the medical literature.

METHODS:

Published on: 
Sep-2015

http://www.ncbi.nlm.nih.gov/pubmed/26049710

. Cirrhosis

Deltenre P, Trépo E, Rudler M, Monescillo A, Fraga M, Denys A, Doerig C, Fournier N, Moreno C, Moradpour D, Bureau C, Thabut D.
Early Transjugular intrahepatic portosystemic shunt in cirrhotic patients with acute variceal bleeding: a systematic review and meta-analysis of controlled trials. Eur J Gastroenterol Hepatol. 2015 Sep;27(9):e1-9.

Abstract

INTRODUCTION:
There is conflicting evidence on the benefit of early transjugular intrahepatic portosystemic shunt (TIPSS) on the survival of patients with acute variceal bleeding (AVB).

AIM:
To assess the effect of early TIPSS on patient prognosis.
MATERIALS AND METHODS:
We carried out a meta-analysis of trials evaluating early TIPSS in cirrhotic patients with AVB.

Published on: 
Sep-2015

What is an 'Liver Function Test?

These are a group of blood tests which reflect the function of the liver. Abnormalities in these tests are helpful in determining the type and extent of damage to the liver if any.

 

What constitutes an LFT?

The following tests constitute an LFT:

  • serum bilirubin-total, direct, indirect

  • serum enzymes- ALT(earlier called as- SGPT), AST (earlier called as- SGOT)

  • serum GGT

  • serum Alkaline phosphatase

  • serum albumin

  • Prothrombin time / international normalization ratio (PT/INR)

 

 

CLF Intro movie

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