Event Videos

http://www.ncbi.nlm.nih.gov/pubmed/25633496

Teng J, Arnell H, Bohlin K, Nemeth A, Fischler B. Impact of parenteral fat composition on cholestasis in preterm infants. J Pediatr Gastroenterol Nutr. 2015 Jun; 60(6):702-7.

Abstract

OBJECTIVES:

Parenteral nutrition-associated liver disease (PNALD) is frequently detected in neonatal intensive care units. Parenteral lipid emulsion (PLE) content has been implicated in its pathogenesis. We aimed to study the effect on incidence and outcome of PNALD by replacing soy-based PLE with olive oil-based PLE in a population-based group of preterm infants.

METHODS:

Published on: 
Jun-2015

http://www.ncbi.nlm.nih.gov/pubmed/25822865

El-Araby HA, Ehsan NA, Konsowa HA, Abd-Elaati BM, Sira AM. Hepatic progenitor cells in children with chronic hepatitis C: correlation with histopathology, viremia, and treatment response. Eur J Gastroenterol Hepatol. 2015 May; 27(5):561-9.

Abstract

OBJECTIVE:
Hepatic progenitor cells (HPCs) are bipotential stem cells that can differentiate towards the hepatocytic and cholangiocytic lineages. Many studies have investigated HPCs in adults with hepatitis C virus infection; however, none has been carried out in the pediatric population. Therefore, this work aimed to investigate HPCs expansion in children with chronic hepatitis C (CHC) and its correlation with histopathology, viremia, and treatment response.

PATIENTS AND METHODS:

Published on: 
May-2015

 

  • What is tyrosinemia?

Tyrosinemia is an inborn error or metabolism i.e., a genetic error in the breakdown of an  amino acid called tyrosine. Due to the error in breakdown, tyrosine and certain by-products accumulate in the body and cause the various disease manifestations.

http://www.ncbi.nlm.nih.gov/pubmed/25522307

Shang XR, Song JY, Liu FH, Ma J, Wang HJ. GWAS-Identified Common Variants With Nonalcoholic Fatty Liver Disease in Chinese Children. J Pediatr Gastroenterol Nutr. 2015 May; 60(5):669-74.

Abstract

OBJECTIVES:

Three genome-wide association studies were previously done for nonalcoholic fatty liver disease (NAFLD) among individuals of Western countries and identified several genetic variants associated with NAFLD. The study aimed to identify whether 7 GWAS-identified common variants (GCKR rs780094, PDGFA rs343064, FDFT1 rs2645424, COL13A1 rs1227756, EHBP1L1 rs6591182, NCAN rs2228603, and PNPLA3 rs738409) were associated with NAFLD in Chinese children.

METHODS:

Published on: 
May-2015

http://www.ncbi.nlm.nih.gov/pubmed/25896839
.- HepatitisB (http://www.childrenliverindia.org/diseases/term/40)

Schillie S, Walker T, Veselsky S, Crowley S, Dusek C, Lazaroff J, Morris SA, Onye K, Ko S, Fenlon N, Nelson NP, Murphy TV. Outcomes of infants born to women infected with hepatitis B. Pediatrics. 2015 May; 135(5):e1141-7.

Abstract

BACKGROUND AND OBJECTIVES:
Perinatal exposure is an important mode of hepatitis B virus (HBV) transmission, resulting in chronic disease in ∼90% of infected infants. Immunoprophylaxis recommended for infants born to hepatitis B surface antigen-positive mothers reduces up to 95% of perinatal HBV infections. We sought to identify factors associated with perinatal HBV transmission.

METHODS:

Published on: 
May-2015

http://www.ncbi.nlm.nih.gov/pubmed/25909866

Duché M, Ducot B, Ackermann O, Jacquemin E, Bernard O. Progression to high-risk gastroesophageal varices in children with biliary atresia with low-risk signs at first endoscopy. J Pediatr Gastroenterol Nutr. 2015 May; 60(5):664-8.

Abstract
OBJECTIVES:

Biliary atresia carries a risk of bleeding because of portal hypertension. Our goal was to define the factors associated with the emergence of endoscopic signs carrying a high risk of bleeding in children who did not display these signs at the first upper gastrointestinal endoscopy.

METHODS:

Published on: 
May-2015

http://www.ncbi.nlm.nih.gov/pubmed/25564820

Ye W, Rosenthal P, Magee JC, Whitington PF; Childhood Liver Disease Research and Education Network. Factors Determining δ-Bilirubin Levels in Infants With Biliary Atresia. J Pediatr Gastroenterol Nutr. 2015 May; 60(5):659-63.

Abstract

OBJECTIVES:
δ-Bilirubin (Bδ) forms when bilirubin conjugates covalently bind to albumin by way of nonenzymatic transesterification in patients with cholestasis. Infants with cholestasis with biliary atresia form Bδ. The aim of the present study was to investigate the factors determining serum Bδ concentrations in infants with biliary atresia.

METHODS:

Published on: 
May-2015

http://www.ncbi.nlm.nih.gov/pubmed/25822855
Acute gastrointestinal bleeding - a new approach to clinical and endoscopic management.- EHPVO-(http://www.childrenliverindia.org/diseases/term/96)
Rey JW, Fischbach A, Teubner D, Dieroff M, Heuberger D, Nguyen-Tat M, Manner H, Kiesslich R, Hoffman A. Acute gastrointestinal bleeding - a new approach to clinical and endoscopic management. Eur J Gastroenterol Hepatol. 2015 May; 27(5):483-91.

Abstract

Published on: 
May-2015

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