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Clinical zinc deficiency as early presentation of Wilson disease http://www.ncbi.nlm.nih.gov/pubmed/25825851 Van Biervliet S, Küry S, De Bruyne R, Vanakker OM, Schmitt S, VandeVelde S,Blouin E, Bézieau S. Clinical zinc deficiency as early presentation of Wilsondisease. J PediatrGastroenterolNutr. 2015;60(4):457-9. Abstract Wilson disease is a rare autosomal recessive disorder of the copper metabolism caused by homozygous or compound heterozygous mutations in the ATP-aseCu(2+) transporting polypeptide (ATP7B) gene. The copper accumulation in different organs leads to the suspicion of Wilson disease. We describe a child with clinical zinc deficiency as presenting symptom of Wilson disease, which was confirmed by 2 mutations within the ATP7B gene and an increased copper excretion. Published on: Apr-2015	Universal infant immunization and occult hepatitis B virus infection in children and adolescents: A population-based study http://www.ncbi.nlm.nih.gov/pubmed/25501911 Hsu HY, Chang MH, Ni YH, Chiang CL, Wu JF, Chen HL. Universal infant immunization and occult hepatitis B virus infection in children and adolescents: A population-based study. Hepatology. 2015; 61(4):1183-91. Abstract Published on: Apr-2015 Read more
Adeno-associated virus vector-based gene therapy for monogenetic metabolic diseases of the liver. http://www.ncbi.nlm.nih.gov/pubmed/25594875 Junge N, Mingozzi F, Ott M, Baumann U. Adeno-associated virus vector-basedgene therapy for monogenetic metabolic diseases of the liver. J PediatrGastroenterolNutr. 2015;60(4):433-40. Abstract Published on: Apr-2015 Read more	Diagnosis and management of acute kidney injury in patients with cirrhosis : revised consensus recommendations of the International Club of Ascites. http://www.ncbi.nlm.nih.gov/pubmed/25631669 Angeli P, Gines P, Wong F, Bernardi M, Boyer TD, Gerbes A, Moreau R, Jalan R, Sarin SK, Piano S, Moore K, Lee SS, Durand F, Salerno F, Caraceni P, Kim WR, Arroyo V, Garcia-Tsao G. Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites. Gut. 2015; 64(4):531-7. Published on: Apr-2015
Dried blood spot in the genotyping,quantification and storage of HCV RNA: a systematic literature review. http://www.ncbi.nlm.nih.gov/pubmed/25367722 Greenman J, Roberts T, Cohn J, Messac L. Dried blood spot in the genotyping,quantification and storage of HCV RNA: a systematic literature review. J ViralHepat. 2015;22(4):353-61. Abstract Published on: Apr-2015 Read more	Hepatoblastoma What is Hepatoblastoma? Hepatoblastoma is a rare tumor of liver. It is however the most common cancerous liver tumor in early childhood. Usually affects children younger than 3 years more so younger than 18 months. The frequency is more in low birth weight babies. Read more
Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis http://www.ncbi.nlm.nih.gov/pubmed/25557690 Sanyal AJ, Friedman SL, McCullough AJ, Dimick-Santos L. Challenges andopportunities in drug and biomarker development for nonalcoholic steatohepatitis: Findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop. Hepatology. 2015; 61(4):1392-405. Abstract Published on: Apr-2015 Read more	Surveillance for infectious complications in pediatric acute liver failure - a prospective study http://www.ncbi.nlm.nih.gov/pubmed/24944144 Mekala S, Jagadisan B, Parija SC, Lakshminarayanan S. Surveillance for infectious complications in pediatric acute liver failure - a prospective study. Indian J Pediatr. 2015 Mar; 82(3):260-6. Abstract OBJECTIVE: To prospectively evaluate infectious complications (IC) in pediatric acute liver failure (PALF) by employing surveillance cultures. METHODS: From 2011 to 2013, children with PALF in a tertiary care centre received a standard protocolised management. Prophylactic parenteral antibiotics were used without antifungals. Surveillance cultures of blood, urine, ascites and tracheal aspirates were sent. Biochemical and clinical parameters and outcomes were compared between children with and without IC. RESULTS: Published on: Mar-2015 Read more
High liver fibrosis index FIB-4 is highly predictive of hepatocellular carcinoma in chronic hepatitis B carriers http://www.ncbi.nlm.nih.gov/pubmed/25502481 Suh B, Park S, Shin DW, Yun JM, Yang HK, Yu SJ, Shin CI, Kim JS, Ahn E, Lee H,Park JH, Cho B. High liver fibrosis index FIB-4 is highly predictive of hepatocellular carcinoma in chronic hepatitis B carriers. Hepatology. 2015; 61(4):1261-8. Abstract Published on: Apr-2015 Read more	Occult HBV infection in multi transfused thalassemia patients http://www.ncbi.nlm.nih.gov/pubmed/24928107 Sabat J, Dwibedi B, Dash L, Kar SK. Occult HBV infection in multi transfused thalassemia patients. Indian J Pediatr. 2015 Mar; 82(3):240-4. Abstract OBJECTIVE: To determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in multitransfused thalassemic patients, with an aim to further highlight the need for donor screening strategy with supplementary molecular diagnostic tools for high risk population. METHODS: The study was conducted in 174 thalassemic subjects from Thalassemia unit of Central Red Cross Blood Bank, Cuttack, Odisha, India. Sero molecular diagnosis was followed to detect antigen, antibody and DNA in the study subjects. RESULTS: Published on: Mar-2015 Read more

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