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Biliary Atresia: Clinical Lessons Learned http://www.ncbi.nlm.nih.gov/pubmed/25658057 - billiary atresia Feldman AG, Mack CL. Biliary Atresia: Clinical Lessons Learned. J Pediatr Gastroenterol Nutr. 2015 Aug; 61(2):167-75. Abstract Published on: Aug-2015 Read more	EASL Recommendations on Treatment of Hepatitis C 2015 http://www.ncbi.nlm.nih.gov/pubmed/25911336 European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu. EASL Recommendations on Treatment of Hepatitis C 2015. J Hepatol. 2015 Jul; 63(1):199-236. Published on: Jul-2015
Fellow patients to share rare drug with Pakistan teenager Sun, 30 Aug 2015 Aayushi Pratap htmetro@hindustantimes.com Fellow patients to share rare drug with Pakistan teenager A group of patients, who attended a gathering on Wilson’s Disease at the Tata Memorial Hospital, have volunteered to give her (Saba Ahmed) the tablets after learning about her struggles. DR ABHA NAGRAL MUMBAI: Doctors at Jaslok Hospital, Peddar Road, will finally be able to give Pakistan citizen Saba Ahmed a new drug after she was unable to tolerate the standard drug given to most Wilson’s Disease patients. Read more	Hepatic steatosis in Wilson disease - Role of copper and PNPLA3 mutations http://www.ncbi.nlm.nih.gov/pubmed/25678388 Stättermayer AF, Traussnigg S, Dienes HP, Aigner E, Stauber R, Lackner K, Hofer H, Stift J, Wrba F, Stadlmayr A, Datz C, Strasser M, Maieron A, Trauner M, Ferenci P. Hepatic steatosis in Wilson disease - Role of copper and PNPLA3 mutations. J Hepatol. 2015 Jul; 63(1):156-63. Abstract BACKGROUND & AIMS: Published on: Jul-2015 Read more
Pak girl’s health improving, attends support group meet \| Press Coverage August 30, 2015 Source/ Reference : http://timesofindia.indiatimes.com/city/mumbai/Pak-girls-health-improvin... TNN \| Aug 30, 2015 Mumbai: Saba Ahmed, the 15-year-old Pakistani girl who was rushed to Mumbai due to complications of a rare genetic disorder, was well enough within a week to attend a support group meeting on Saturday. Ordinary Mumbaikars raised over Rs 3.5 lakh through a crowd-funding effort to help the teenager fly into Mumbai last week from Karachi for treatment of Wilson's Disease. Her mother Nazia said, "We found out she had Wilson's disease 18 months ago. When doctors back home told me that Saba would never again speak or walk, we came to Mumbai." Read more	Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice http://www.ncbi.nlm.nih.gov/pubmed/25681557 drug induced liver injury Kim YH, Hwang JH, Kim KS, Noh JR, Choi DH, Kim DK, Tadi S, Yim YH, Choi HS, Lee CH. Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice. J Hepatol. 2015 Jul; 63(1):75-82. Abstract BACKGROUND & AIMS: Published on: Jul-2015 Read more
Efficacy of rifaximin on circulating endotoxins and cytokines in patients with non-alcoholic fatty liver disease http://www.ncbi.nlm.nih.gov/pubmed/26043290 Gangarapu V, Ince AT, Baysal B, Kayar Y, Kılıç U, Gök Ö, Uysal Ö, Şenturk H. Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease. Eur J Gastroenterol Hepatol. 2015 Jul;27(7):840-5. Abstract OBJECTIVE: Recent studies have suggested that endotoxin-induced cytokines play an important role in nonalcoholic fatty liver disease (NAFLD). Rifaximin is a nonabsorbable antibiotic that might act on Gram-negative bacteria, thereby inhibiting endotoxin proinflammatory cytokine production in patients with NAFLD. Our aim was to investigate the efficacy of rifaximin on NAFLD. METHODS: Published on: Jul-2015 Read more	Non-selective β-blockers are associated with improved survival in patients with ascites listed for liver transplantation http://www.ncbi.nlm.nih.gov/pubmed/25281417 Leithead JA, Rajoriya N, Tehami N, Hodson J, Gunson BK, Tripathi D, Ferguson JW. Non-selective β-blockers are associated with improved survival in patients with ascites listed for liver transplantation. Gut. 2015 Jul;64(7):1111-9. Abstract OBJECTIVE: Recent data have suggested that non-selective β-blockers (NSBB) are associated with increased mortality in patients with cirrhosis and refractory ascites. However, other evidence implies that NSBB may be beneficial in this setting by reducing bacterial translocation. Our aim was to determine whether NSBB use was a risk factor for mortality in patients with end-stage chronic liver disease and ascites awaiting liver transplantation. DESIGN: Published on: Jul-2015 Read more
Usefulness of indirect noninvasive methods in predicting progression to cirrhosis in chronic hepatitis C http://www.ncbi.nlm.nih.gov/pubmed/26043289 Vergara M, Bejarano G, Dalmau B, Gil M, Miquel M, Sanchez-Delgado J, Casas M, Puig J, Martinez-Bauer E, Dosal A, Lopez M, Moreno L, Valero O, Bella MR, Calvet X. Usefulness of indirect noninvasive methods in predicting progression to cirrhosis in chronic hepatitis C. Eur J Gastroenterol Hepatol. 2015 Jul;27(7):826-33. Abstract BACKGROUND AND AIMS: The ability of noninvasive methods to predict the development of cirrhosis has not been established. We evaluated the ability of three noninvasive methods [the Forns index, the aspartate aminotransferase-to-platelet ratio index (APRI), and the Non-Invasive Hepatitis-C-related Cirrhosis Early Detection (NIHCED) score] to determine the risk of developing cirrhosis in chronic hepatitis C. Published on: Jul-2015 Read more	Increase of Serum γ-Glutamyltransferase Associated With Development of Cirrhotic Cystic Fibrosis Liver Disease http://www.ncbi.nlm.nih.gov/pubmed/25658056 Bodewes FA, van der Doef HP, Houwen RH, Verkade HJ. Increase of Serum γ-Glutamyltransferase Associated With Development of Cirrhotic Cystic Fibrosis Liver Disease. J Pediatr Gastroenterol Nutr. 2015 Jul;61(1):113-8. Abstract BACKGROUND: Identification of patients at risk for developing cirrhotic cystic fibrosis liver disease (CCFLD) is essential for targeting potentially preventive treatment. We studied the evolution of serum liver enzymes and thrombocyte counts as predictors of CCFLD development. METHODS: Published on: Jul-2015 Read more

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