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Extra Hepatic Portal Venous Obstruction (EHPVO) FAQ on Extra Hepatic Portal Venous Obstruction (EHPVO) 1. What is EHPVO? EHPVO is a condition in which there is a block of the major vessel that supplies blood to the liver i.e. the portal vein. This vein carries all absorbed nutrients from intestines to liver for storage and further metabolism. It accounts for major (80%) of blood supply to liver. Any block in this vein especially in the portion of the vein located outside the liver causes a condition called as EHPVO. 2. What causes EHPVO? EHPVO or the block in the portal vein may be caused by: Read more	Occult hepatitis B infection in children with chronic liver disease http://www.ncbi.nlm.nih.gov/pubmed/25874508 Srivastava A, Mathias A, Yachha SK, Aggarwal R. Occult hepatitis B infectionin children with chronic liver disease. Eur J GastroenterolHepatol. 2015; 27(4):375-7. Abstract AIMS: Occult hepatitis B infection (OBI) may adversely affect the outcome of patients with chronic liver disease (CLD). There are no data on OBI and CLD in children. This study determined the prevalence and effect of OBI in HBsAg-negative CLD children. MATERIALS AND METHODS: CLD children were prospectively evaluated with a demographic, clinical, and investigative proforma. All HBsAg-negative CLD cases were tested for exposure to hepatitis B (total anti-HBc, anti-HBs). Serum hepatitis B virus DNA was measured in exposed (total anti-HBc positive) patients. Published on: Apr-2015 Read more
Financial support for vaccination in India till 2020: Gavi Surce : http://zeenews.india.com/news/health/health-news/financial-support-for-v... India will continue to get financial assistance from Gavi, a global alliance for vaccination and immunisation, only till 2020 because as the country develops it will have to pay for its vaccines. Switzerland-based Gavi is on a drive to increase its global immunisation programme in which India has been an important partner. "India is getting to a point where it will enter the period of graduating from Gavi's support, probably in 2016," Gavi Chief Executive Officer Seth Berkley told PTI. Read more	Clinical zinc deficiency as early presentation of Wilson disease http://www.ncbi.nlm.nih.gov/pubmed/25825851 Van Biervliet S, Küry S, De Bruyne R, Vanakker OM, Schmitt S, VandeVelde S,Blouin E, Bézieau S. Clinical zinc deficiency as early presentation of Wilsondisease. J PediatrGastroenterolNutr. 2015;60(4):457-9. Abstract Wilson disease is a rare autosomal recessive disorder of the copper metabolism caused by homozygous or compound heterozygous mutations in the ATP-aseCu(2+) transporting polypeptide (ATP7B) gene. The copper accumulation in different organs leads to the suspicion of Wilson disease. We describe a child with clinical zinc deficiency as presenting symptom of Wilson disease, which was confirmed by 2 mutations within the ATP7B gene and an increased copper excretion. Published on: Apr-2015
Hepatitis-c drugs added to WHO list of essential medicines source : http://www.nytimes.com/2015/05/09/health/hepatitis-c-drugs-added-to-who-...	Adeno-associated virus vector-based gene therapy for monogenetic metabolic diseases of the liver. http://www.ncbi.nlm.nih.gov/pubmed/25594875 Junge N, Mingozzi F, Ott M, Baumann U. Adeno-associated virus vector-basedgene therapy for monogenetic metabolic diseases of the liver. J PediatrGastroenterolNutr. 2015;60(4):433-40. Abstract Published on: Apr-2015 Read more
List of Pediatric Gastroenterologist India Chandigarh Dr. BR Thapa Professor and Head, Division of Pediatric Gastroenterology, Hepatology and nutrition, PGIMER, Chandigarh Delhi Dr. Seema Alam Additional Professor Department of Pediatric Hepatology Institue of Liver and Billiary Sciences, New Delhi Dr. Dinesh Rawat Department of Pediatric Hepatology Institue of Liver and Billiary Sciences, New Delhi Dr. Anupam Sibal Read more	Dried blood spot in the genotyping,quantification and storage of HCV RNA: a systematic literature review. http://www.ncbi.nlm.nih.gov/pubmed/25367722 Greenman J, Roberts T, Cohn J, Messac L. Dried blood spot in the genotyping,quantification and storage of HCV RNA: a systematic literature review. J ViralHepat. 2015;22(4):353-61. Abstract Published on: Apr-2015 Read more
Comparison of 2 days versus 5 days of octreotide infusion along with endoscopic therapy in preventing early rebleed from esophageal varices: a randomized clinical study http://www.ncbi.nlm.nih.gov/pubmed/25874510 Rengasamy S, Ali SM, Sistla SC, Lakshmi CP, Harichandra Kumar KT. Comparisonof 2 days versus 5 days of octreotide infusion along with endoscopic therapy in preventing early rebleed from esophageal varices: a randomized clinical study. Eur J GastroenterolHepatol. 2015; 27(4):386-92. Abstract BACKGROUND: Published on: Apr-2015 Read more	Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis http://www.ncbi.nlm.nih.gov/pubmed/25557690 Sanyal AJ, Friedman SL, McCullough AJ, Dimick-Santos L. Challenges andopportunities in drug and biomarker development for nonalcoholic steatohepatitis: Findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop. Hepatology. 2015; 61(4):1392-405. Abstract Published on: Apr-2015 Read more

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