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http://www.ncbi.nlm.nih.gov/pubmed/24122953

Pugliese R, Fonseca EA, Porta G, Danesi V, Guimaraes T, Porta A, Miura IK, Borges C, Candido H, Benavides M, Feier FH, Godoy A, Cardoso RA, Kondo M, Chapchap P, Neto JS. Ascites and serum sodium are markers of increased waiting list mortality in children with chronic liver failure. Hepatology. 2014 May; 59(5):1964-71.
Abstract

Published on: 
Jun-2014

What is Hepatitis A?

Hepatitis A is an infection of the liver caused by a virus called Hepatitis A virus.

How does this disease spread?

Hepatitis A is an enterally transmitted disease that is it is food borne. It spreads from one to another through contaminated food or water.

Naim Alkhouri, Sana Mansoor, Paola Giammaria, Rocio Lopez, Valerio Nobili,
Gastroenterology 2014 May; 146 (7): s 40
http://www.gastrojournal.org/article/S0016-5085%2814%2960040-8/pdf

Background:

Noninvasive hepatic fibrosis scores that predict the presence of advanced fibrosis have been developed and validated in adult patients with NAFLD. There is an urgent need to test and develop similar scores in children with NAFLD. The aim of our study was to assess the utility of commonly used adult fibrosis scores in pediatric NAFLD and to develop a pediatric specific fibrosis score that can predict advanced fibrosis.

Methods:

Published on: 
May-2014

FDA and EMA Join Forces on Treatment of Gaucher Disease in Children
http://www.pharmtech.com/pharmtech/News/FDA-and-EMA-Join-Forces-on-Treat...

FDA and the European Medicines Agency (EMA) released a draft joint proposal to facilitate research in the development of new drugs to treat Gaucher disease in children. The proposal, the result of consultation with various groups of stakeholders, facilitates an agreement between an FDA Pediatric Study Plan and an EMA Paediatric Investigation Plan and addresses the development of drugs for rare diseases in a reduced timeframe in a limited number of patients.

http://www.ncbi.nlm.nih.gov/pubmed/24732866

Muir AJ. The rapid evolution of treatment strategies for hepatitis C. Am J Gastroenterol. 2014 May; 109(5):628-35.

Abstract

Hepatitis C virus (HCV) treatment took a major step forward at the end of 2013 with the approvals of the second-generation protease inhibitor Simeprevir (Olysio) and the nucleotide polymerase inhibitor Sofosbuvir (Sovaldi). The interferon-free regimen of Sofosbuvir and ribavirin is now available for genotype 2 and 3 patients. This regimen for 12 weeks is highly effective for genotype 2, whereas genotype 3 has proven to be more challenging and requires 24 weeks of therapy. Genotype 1 patients have reduced exposure to peginterferon-α with a 12-week regimen with sofosbuvir and a 24-week regimen with Simeprevir.

Published on: 
Jun-2014

KOLKATA: Kids, beware. The next time you gorge on junk food, keep in mind that those burgers and rolls are pushing you to a point of no return.
According to a study conducted by Diabetes Awareness and You (DAY) - a platform of clinical specialists - children in the city now have a weaker liver and are more prone to diseases than they were 15 years ago. An alarming 12-15% of kids and adolescents between 12 and 16 years of age suffer from fatty liver. It can eventually lead to more serious and life-threatening ailments like cirrhosis and liver cancer. While fat-rich food and a sedentary lifestyle are being blamed for the threat, doctors warn that liver diseases could be the second most common ailment in the city, after fdiabetes, in another 15 years.

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