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Our vitamin D needs are met from the nutrients we consume and a hormone produced in the body. A new study says that a low status of vitamin D triggers non-alcoholic fatty liver disease in children.
Researchers at the King's College Hospital Paediatric Liver Centre in collaboration with University of Surrey's School of Biosciences and Medicine investigated the link between low level of Vitamin D and non alcoholic fatty liver disease (NAFLD) in the U.K. children and found a genetic variant associated with the severity of the disease. For this study, the researchers analysed the medical records of over 120 paediatric patients with NAFLD.
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http://www.ncbi.nlm.nih.gov/pubmed/24492755 Theocharidou E, Pieri G, Mohammad AO, Cheung M, Cholongitas E, Banwari A, Burroughs AK. The Royal Free Hospital Score: A Calibrated Prognostic Model for Patients With Cirrhosis Admitted to Intensive Care Unit. Comparison with Current Models and CLIF-SOFA Score. Am J Gastroenterol. 2014 Apr; 109(4): 554-62. Abstract OBJECTIVES: Published on:
Apr-2014
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Dr Seema Alam Dr Vidyut Bhatia, Dr. V S Sankarnarayan, Dr Aabha Nagral, MD, DNB |
http://www.ncbi.nlm.nih.gov/pubmed/24423432 Deneau M, Book LS, Guthery SL, Jensen MK. Outcome after discontinuation of Immune-suppression in children with autoimmune hepatitis: a population-based study. J Pediatr. 2014 Apr; 164(4): 714-719. Abstract OBJECTIVE: To assess sustained immunosuppression-free remission (SIFR) in children with autoimmune hepatitis (AIH). STUDY DESIGN: We retrospectively reviewed all children with AIH in the region between 1986 and 2011 using a population-based methodology. RESULTS: Published on:
Apr-2014
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Centre for Human GeneticsDr Meenakshi Bhat, Institute of Human GeneticsFrigeHouse, NIRMANDr. Anil B. Jalan |
http://www.ncbi.nlm.nih.gov/pubmed/24360992 Molleston JP, Schwimmer JB, Yates KP, Murray KF, Cummings OW, Lavine JE, Brunt Abstract OBJECTIVE: To investigate the histological spectrum of nonalcoholic fatty liver disease (NAFLD) in children with normal, mildly elevated (26-50 U/L boys, 23-44 U/L girls), or elevated (>50 U/L in boys, >44 U/L in girls) serum alanine aminotransferase (ALT) levels. STUDY DESIGN: Published on:
Apr-2014
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http://www.ncbi.nlm.nih.gov/pubmed/24224950 Miyaoka Y, Amano Y, Ueno S, Izumi D, Mikami H, Yazaki T, Okimoto E, Sonoyama T, Ito S, Fujishiro H, Kohge N, Imaoka T. The role of enhanced multi-detector-row computed tomography before urgent endoscopy in acute upper gastrointestinal bleeding. J Gastroenterol Hepatol. 2014 Apr; 29(4): 716-22. Abstract BACKGROUND AND AIM: Multi-detector-row computed tomography (MDCT) has been reported to be a potentially useful modality for detection of the bleeding origin in patients with acute upper massive gastrointestinal (GI) bleeding. The purpose of this study is to investigate the efficacy of MDCT as a routine method for detecting the origin of acute upper GI bleeding prior to urgent endoscopy. METHODS: Published on:
Apr-2014
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http://www.ncbi.nlm.nih.gov/pubmed/24321532 Sundaram SS, Sokol RJ, Capocelli KE, Pan Z, Sullivan JS, Robbins K, Halbower AC. Obstructive sleep apnea and hypoxemia are associated with advanced liver histology in pediatric nonalcoholic fatty liver disease. J Pediatr. 2014 Apr; 164(4): 699-706. Abstract OBJECTIVE: To determine whether obstructive sleep apnea (OSA) and/or nocturnal hypoxemia are associated with the severity of liver injury in patients with pediatric nonalcoholic fatty liver disease (NAFLD). STUDY DESIGN: Published on:
Apr-2014
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http://www.ncbi.nlm.nih.gov/pubmed/24117967 Qi X, Liu L, Bai M, Chen H, Wang J, Yang Z, Han G, Fan D. Transjugular intrahepatic porto-systemic shunt in combination with or without variceal embolization for the prevention of variceal rebleeding: a meta-analysis. J Gastroenterol Hepatol. 2014 Apr; 29(4): 688-96. Abstract BACKGROUND AND AIM: Published on:
Apr-2014
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http://www.ncbi.nlm.nih.gov/pubmed/24231645 Wang P, Su H, Underhill J, Blackmore LJ, Longhi MS, Grammatikopoulos T, Okokon EV, Davies ET, Vergani D, Mieli-Vergani G, Ma Y. Autoantibody and human leukocyte antigen profiles in children with autoimmune liver disease and their first-degree relatives. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):457-62. Abstract OBJECTIVE: Familial clustering of juvenile autoimmune liver disease (AILD), including autoimmune hepatitis and autoimmune sclerosing cholangitis (ASC), is rare, despite a high prevalence of autoimmune disorders in AILD families. METHODS: Published on:
Apr-2014
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