|
|
|
Event Videos
|
http://www.ncbi.nlm.nih.gov/pubmed/24423432 Deneau M, Book LS, Guthery SL, Jensen MK. Outcome after discontinuation of Immune-suppression in children with autoimmune hepatitis: a population-based study. J Pediatr. 2014 Apr; 164(4): 714-719. Abstract OBJECTIVE: To assess sustained immunosuppression-free remission (SIFR) in children with autoimmune hepatitis (AIH). STUDY DESIGN: We retrospectively reviewed all children with AIH in the region between 1986 and 2011 using a population-based methodology. RESULTS: Published on:
Apr-2014
|
American Hepatitis C drug on the market in SeptemberDr. Wahid Doss, head of the National Institute for Liver Diseases, said on Monday said the Health Ministry and the registry of the Central Administration of Pharmaceuticals met to complete the registration of the American Hepatitis C drug. He added that the ministry is buying the drug at 1 percent of its global price.
“Registration will be completed within two months, the fastest period in the history of drug registration in Egypt,” he said. “It will be available on the market in September.”
|
||||
|
http://www.ncbi.nlm.nih.gov/pubmed/24360992 Molleston JP, Schwimmer JB, Yates KP, Murray KF, Cummings OW, Lavine JE, Brunt Abstract OBJECTIVE: To investigate the histological spectrum of nonalcoholic fatty liver disease (NAFLD) in children with normal, mildly elevated (26-50 U/L boys, 23-44 U/L girls), or elevated (>50 U/L in boys, >44 U/L in girls) serum alanine aminotransferase (ALT) levels. STUDY DESIGN: Published on:
Apr-2014
|
What is hepatitis C?Hepatitis C is the disease of the liver caused due to infection by hepatitis C virus (HCV). It is one of the common causes of chronic liver disease and may to progressive liver disease. It is also the leading indication for liver transplantation. How common is hepatitis C infection?It has been estimated that the globally around 2% are infected with HCV. 170 million people are chronically infected the virus. Also 3 to 4 million people get newly infected with the virus each year. In India around 1-2% of people are infected with this virus. The disease is common among children who require multiple transfusions like those suffering from Thalassemia and hemophilia. |
||||
|
http://www.ncbi.nlm.nih.gov/pubmed/24321532 Sundaram SS, Sokol RJ, Capocelli KE, Pan Z, Sullivan JS, Robbins K, Halbower AC. Obstructive sleep apnea and hypoxemia are associated with advanced liver histology in pediatric nonalcoholic fatty liver disease. J Pediatr. 2014 Apr; 164(4): 699-706. Abstract OBJECTIVE: To determine whether obstructive sleep apnea (OSA) and/or nocturnal hypoxemia are associated with the severity of liver injury in patients with pediatric nonalcoholic fatty liver disease (NAFLD). STUDY DESIGN: Published on:
Apr-2014
|
What is Budd Chiari syndrome?Budd chiari syndrome (BCS) is a disease characterized by obstruction of the hepatic venous outflow tract which is the main channel taking blood from the liver to the heart. Liver receives the blood supply from the portal vein and hepatic artery. After circulating through the liver, the blood then flows out via the hepatic veins to the inferior vena cava (large blood vessel emptying into the heart). There are total three hepatic veins. The obstruction to the blood flow can be in the hepatic veins or in the inferior vena cava. If the obstruction is in the smaller veins of liver (hepatic venules), then it is called as sinusoidal obstruction syndrome. |
||||
|
http://www.ncbi.nlm.nih.gov/pubmed/24231645 Wang P, Su H, Underhill J, Blackmore LJ, Longhi MS, Grammatikopoulos T, Okokon EV, Davies ET, Vergani D, Mieli-Vergani G, Ma Y. Autoantibody and human leukocyte antigen profiles in children with autoimmune liver disease and their first-degree relatives. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):457-62. Abstract OBJECTIVE: Familial clustering of juvenile autoimmune liver disease (AILD), including autoimmune hepatitis and autoimmune sclerosing cholangitis (ASC), is rare, despite a high prevalence of autoimmune disorders in AILD families. METHODS: Published on:
Apr-2014
|
Enzyme therapy proves effective in treating LSDs, whilst gene therapy is an upcoming contender. Lysosomes are membrane-bound organelles found in most animal cells. They are responsible for treating cellular waste. Genetic mutations in lysosomal enzymes lead to lysosome malfunction and waste accumulation. And this leads to a whole range of complex metabolic disorders, collectively called Lysosomal Storage Diseases (LSD). There are two kinds of LDSs: those that affect the brain (neuropathic) and those that do not (non-neuropathic). The EU-funded EUCLYD project, completed in 2011, studied four non-neuropathic LSDs out of the 50 currently known. These were Gaucher disease, Pompe disease, the mucopolysaccharidosis (MPS) VI and the multiple sulfatase deficiency. |
||||
|
http://www.ncbi.nlm.nih.gov/pubmed/24345828 Hussain E, Grimason M, Goldstein J, Smith CM, Alonso E, Whitington PF, Wainwright MS. EEG abnormalities are associated with increased risk of transplant or poor outcome in children with acute liver failure. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4): 449-56. Abstract OBJECTIVES: There are limited data on the incidence of seizures and utility of brain imaging and electroencephalogram (EEG) to predict outcome of children with acute liver failure (ALF). We investigated the association between hepatic encephalopathy (HE) scores, abnormal EEG or neuroimaging, and short-term outcome. METHODS: Published on:
Apr-2014
|
Treatment guidelines for virus highlight challenge of paying for expensive drugs in low-income countries.
Campaigners in India have been calling for access to cheap hepatitis C treatments. The publication last week of the first treatment guidelines for hepatitis C virus (HCV), and the advent of drugs that can cure most infections of the virus, have left public-health researchers with a touch of déjà vu.
Three decades after wrestling to lower the cost of AIDS drugs (prices fell from about US$10,000 per patient per year in the 1990s to less than $100 in the mid-2000s), they are once again asking how expensive life-saving medicines can be made affordable for patients.
|
SMS requests to
9224791366
Ask The Expert
Pediatric Liver Specialists in India
Centres offering Genetic Testing for Pediatric Liver Diseases
Financial Aid Offered by Trusts
