Event Videos

J Gastroenterol Hepatol. 2013 Jul;28(7):1202-8.
Salomone F, Li Volti G, Rosso C, Grosso G, Bugianesi E.
http://www.ncbi.nlm.nih.gov/pubmed/23425054

Abstract
Background and Aim: Oxidative stress is considered a key element in the progression of
non-alcoholic fatty liver to non-alcoholic steatohepatitis (NASH). Unconjugated bilirubin
is the main endogenous lipid antioxidant and is cytoprotective in different tissues and
organs. In this study, it was evaluated if unconjugated bilirubin levels are associated with
the degree of liver injury in patients with non-alcoholic fatty liver disease.
Methods: Two hundred and eighty-five patients were retrospectively evaluated with

Published on: 
Jul-2013

Hepatology. 2013 Jun;57(6):2124-34
Grebely J, Feld JJ, Applegate T, Matthews GV, Hellard M, Sherker A, Petoumenos K, Zang G,  Shaw I, Yeung B, George J, Teutsch S, Kaldor JM, Cherepanov V, Bruneau J, Shoukry NH, Lloyd AR, Dore GJ.
http://www.ncbi.nlm.nih.gov/pubmed/23325615

Systemic levels of interferon-gamma-inducible protein-10 (IP-10) are predictive of treatment-
induced clearance in chronic hepatitis C virus (HCV). In the present study, factors
associated with plasma IP-10 levels at the time of acute HCV detection and the association
between IP-10 levels and spontaneous clearance were assessed in three cohorts of acute HCV

Published on: 
Jun-2013

J Clin Gastroenterol. 2013 Jul;47(6):553-8.
Ghabril M, Fontana R, Rockey D, Jiezhun G, Chalasani N.
http://www.ncbi.nlm.nih.gov/pubmed/23388845

Background and Aims: Idiosyncratic drug-induced liver injury (DILI) can be caused by intravenous (IV) medications, but the characteristics of DILI caused by these agents are not known. The aim of this study is to characterize the clinical features of subjects with suspected DILI associated with IV agents enrolled into the Drug Induced Liver Injury Network Prospective Study.

Methods: Subjects with suspected DILI due to IV medications with probable, highly likely, or definite casuality scores were eligible.

Published on: 
Jul-2013

A Multicenter Case-Control Study
            Hepatology. 2013 Jun;57(6):2117-23
            Carney K, Dhalla S, Aytaman A, Tenner CT, Francois F.
            http://www.ncbi.nlm.nih.gov/pubmed/23315899

Although injection drug use (IDU) and blood transfusions prior to 1992 are well-accepted
risk factors for hepatitis C virus (HCV) infection, many studies that evaluated tattooing as
a risk factor for HCV infection did not control for a history of IDU or transfusion prior to
1992. In this large, multicenter, case-control study, we analyzed demographic and HCV

Published on: 
Jun-2013

J Clin Gastroenterol 2013 Jul ;47:545–552

Tyson GL, Richardson PA, White DL, Kuzniarek J, Ramsey DJ, Tavakoli-Tabasi S, El-Serag HB.

http://www.ncbi.nlm.nih.gov/pubmed/23426443

Background and Goals: Dietary fructose intake in the United States has been increasing, and fructose intake has been associated with the metabolic syndrome and hepatic steatosis. This study aimed to determine whether dietary fructose intake is associated with advanced hepatic fibrosis and inflammation in an hepatitis C virus (HCV)-infected male population.

Published on: 
Jul-2013

Hepatology. 2013 Jun;57(6):2539-41.
Moghadamrad S, Montani M, Weimann R, De Gottardi A.
http://www.ncbi.nlm.nih.gov/pubmed/23446990

Cholestasis with normal gamma glutamyl transferase characterizes functional deficiencies
in the gene ABCB11, which encodes the bile salt export pump (BSEP), a liver-specific
adenosine triphosphate (ATP)-binding cassette transporter. Here we report the case of a
patient presenting with features of benign recurrent intrahepatic cholestasis associated
with a heterozygous mutation in the ABCB11 gene. Immunohistochemistry showed a
gradual decrease of BSEP from zone 1 to zone 3 of the liver lobule, suggesting that the

Published on: 
Jun-2013

Am J Gastroenterol. 2013 Jun;108(6):942-8.
Fung J, Chan SC, Cheung C, Yuen MF, Chok KS, Sharr W, Chan AC, Cheung TT, Seto WK, Fan     ST, Lai CL, Lo CM.
  http://www.ncbi.nlm.nih.gov/pubmed/23629601

OBJECTIVES: The long-term outcomes of oral antiviral therapy without hepatitis B immune globulin (HBIG) in prevention of reinfection with hepatitis B after liver transplantation are not known. We aimed to determine the long-term outcomes from a large population of chronic hepatitis B (CHB) liver transplant recipients using oral antiviral therapy alone.

Published on: 
Jun-2013

CLF Intro movie

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