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Young Om Landge is 10 years old, a bright child fond of cricket and painting. He studies in Santutai English Medium school on the outskirts of Pune.

At the age of 5 he was diagnosed with extra hepatic portal venous obstruction (EHPVO) at a Children's speciality in Pune. This is a  condition wherein the main blood supply to the liver, the portal vein, is blocked and replaced by bypass channels, some of which develop in the food pipe.  These can rupture and cause life threatening blood vomits.

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  1. What is Haemophagocytic lymphohistiocytosis?

Hemophagocyticlymphohistiocytosis (HLH) is a rare but potentially fatal disease of normal but overactive cells calledhistiocytes and lymphocytes that commonly appears in the first year of life, although it has been seen in all age groups.
 

  1. What are the types of HLH?

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What is Gaucher disease?

Gaucher disease is an inherited disorder that affects many of the body's organs and tissues.
The signs and symptoms of this condition vary widely among affected individuals.

How common is Gaucher disease?

Gaucher disease occurs in 1 in 50,000 to 100,000 people in the general population.

How do people inherit Gaucher disease?

What is autoimmune hepatitis?

‘Autoimmune’ is made of two words- ‘auto’ +’immune’- implying altered immunity to cells of one’s own body. Immune system normally recognises ‘self ‘and ‘non-self’ cells. It kills only the ‘non-self’ cells. When there is an alteration in the immune system, it loses this ability to differentiate ‘self’ from ‘non self’; and kills ‘self’ cells.

When such attack of the immune system involves cells of liver, it causes Autoimmune Hepatitis. It may occur as only hepatitis or may occur as a part of other autoimmune diseases.

 

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