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β-Klotho gene variation is associated with liver damage in children with NAFLD https://www.ncbi.nlm.nih.gov/pubmed/31652022 Transplant Pediatr Transplant. 2019 Oct 25:e13608. doi: 10.1111/petr.13608. [Epub ahead of print] The use of urinary biomarkers to predict acute kidney injury in children after liver transplant. Fuhrman DY1,2,3, Kellum JA2, Joyce EL2,3, Miyashita Y3, Mazariegos GV4, Ganoza A4, Squires JE5. Abstract BACKGROUND: AKI after pediatric liver transplantation is associated with increased morbidity and mortality. The role of urinary biomarkers for the prediction of AKI in pediatric patients after liver transplantation has not been previously reported. The primary objective of this prospective pilot study was to determine the predictive capabilities of urinary KIM-1, NGAL, TIMP-2, and IGFBP7 for diagnosing AKI. METHODS: Published on: Oct-2019 Read more	Congenital Portosystemic Shunts in Children: Associations, Complications, and Outcomes https://www.ncbi.nlm.nih.gov/pubmed/31549332 Dig Dis Sci. 2019 Sep 23. doi: 10.1007/s10620-019-05834-w. [Epub ahead of print] Congenital Portosystemic Shunts in Children: Associations, Complications, and Outcomes. DiPaola F1, Trout AT2,3, Walther AE4, Gupta A5, Sheridan R5, Campbell KM6, Tiao G7, Bezerra JA6, Bove KE5, Patel M2,3, Nathan JD7. Abstract BACKGROUND: Published on: Sep-2019 Read more
β-Klotho gene variation is associated with liver damage in children with NAFLD https://www.ncbi.nlm.nih.gov/pubmed/31655133 NAFLD J Hepatol. 2019 Oct 23. pii: S0168-8278(19)30613-0. doi: 10.1016/j.jhep.2019.10.011. β-Klotho gene variation is associated with liver damage in children with NAFLD. Dongiovanni P1, Crudele A2, Panera N3, Romito I4, Meroni M5, De Stefanis C6, Palma A7, Comparcola D8, Fracanzani AL9, Miele L10, Valenti L11, Nobili V12, Alisi A13. Abstract BACKGROUND AND AIM: Published on: Oct-2019 Read more	Band ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis. https://www.ncbi.nlm.nih.gov/pubmed/31550050 Chronic liver disease Cochrane Database Syst Rev. 2019 Sep 24;9:CD010546. doi: 10.1002/14651858.CD010546.pub2. Band ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis. Gana JC1, Cifuentes LI, Gattini D, Villarroel Del Pino LA, Peña A, Torres-Robles R Abstract BACKGROUND: Published on: Sep-2019 Read more
Severe obesity is associated with liver disease severity in pediatric non-alcoholic fatty liver disease https://www.ncbi.nlm.nih.gov/pubmed/31657145 NAFLD Pediatr Obes. 2019 Oct 27. doi: 10.1111/ijpo.12581. [Epub ahead of print] Severe obesity is associated with liver disease severity in pediatric non-alcoholic fatty liver disease. Seth A1, Orkin S2, Yodoshi T2, Liu C3, Fei L3, Hardy J2, Trout AT4, Arce Clachar AC2, Bramlage K2, Xanthakos S2, Mouzaki M2. Abstract BACKGROUND: Paediatric non-alcoholic fatty liver disease (NAFLD) is highly prevalent among children with obesity. The primary objective of this study was determining whether obesity severity is associated with NAFLD severity. By using paediatric classifications for severe obesity, clinicians may be able to better risk stratify patients, which in turn would guide more effective management and treatment. METHODS: Published on: Oct-2019 Read more	Crigler-Najjar syndrome type 1: pathophysiology, natural history, and therapeutic frontier https://www.ncbi.nlm.nih.gov/pubmed/31553814 Neonatal cholestasis Hepatology. 2019 Sep 25. doi: 10.1002/hep.30959. [Epub ahead of print] Crigler-Najjar syndrome type 1: pathophysiology, natural history, and therapeutic frontier. Strauss KA1,2,3, Ahlfors CE4, Soltys K5, Mazareigos GV5, Young M1, Bowser LE1, Fox MD1,6,7, Squires JE8, McKiernan P9, Brigatti KW1, Puffenberger EG1, Carson VJ1, Vreman HJ10. Abstract Published on: Sep-2019 Read more
Updates in the management of hepatitis B in children https://www.ncbi.nlm.nih.gov/pubmed/31663387 Hepatitis B Expert Rev Gastroenterol Hepatol. 2019 Oct 30. doi: 10.1080/17474124.2019.1686975. [Epub ahead of print] Updates in the management of hepatitis B in children. Lai MW1,2,3, Chang MH4. Abstract Published on: Oct-2019 Read more	Role of Soluble Adiponectin Receptor 2 in Non-Alcoholic Fatty Liver Disease in Children. https://www.ncbi.nlm.nih.gov/pubmed/31555572 NAFLD Pediatr Gastroenterol Hepatol Nutr. 2019 Sep;22(5):470-478. doi: 10.5223/pghn.2019.22.5.470. Epub 2019 Sep 11. Role of Soluble Adiponectin Receptor 2 in Non-Alcoholic Fatty Liver Disease in Children. Aksoy GK1, Artan R2, Aksoy C3, Özdem S4, Atalay A2, Yılmaz A2. Abstract PURPOSE: The incidence of non-alcoholic fatty liver disease (NAFLD) in children is gradually increasing. The aim of this study was to investigate the use of serum adiponectin and soluble adiponectin receptor 2 (soluble Adipo R2) levels for the diagnosis of fatty liver disease in obese and overweight children. METHODS: Published on: Sep-2019 Read more
Hepatobiliary Complications in Children with Sickle Cell Disease: A Retrospective Review of Medical Records from 616 Patients. https://www.ncbi.nlm.nih.gov/pubmed/31540390 J Clin Med. 2019 Sep 18;8(9). pii: E1481. doi: 10.3390/jcm8091481. Hepatobiliary Complications in Children with Sickle Cell Disease: A Retrospective Review of Medical Records from 616 Patients. Allali S1,2,3, de Montalembert M4,5, Brousse V6, Heilbronner C7, Taylor M8, Brice J9, Manzali E10, Garcelon N11, Lacaille F12. Abstract Published on: Sep-2019 Read more	Novel ATP8B1 Gene Mutations in a Child with Progressive Familial Intrahepatic Cholestasis Type 1. https://www.ncbi.nlm.nih.gov/pubmed/31555573 PFIC Pediatr Gastroenterol Hepatol Nutr. 2019 Sep;22(5):479-486. doi: 10.5223/pghn.2019.22.5.479. Epub 2019 Sep 11. Novel ATP8B1 Gene Mutations in a Child with Progressive Familial Intrahepatic Cholestasis Type 1. Rhee ES1, Kim YB1, Lee S1, Oh SH1, Lee BH1, Kim KM1, Yoo HW1. Abstract Published on: Sep-2019 Read more

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