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Is Hepatovenocaval Syndrome a Different Entity from Budd-Chiari Syndrome in Children? https://www.ncbi.nlm.nih.gov/pubmed/29690960 Budd Chiari Syndrome J Coll Physicians Surg Pak. 2018 May;28(5):344-347. doi: 10.29271/jcpsp.2018.05.344.Is Hepatovenocaval Syndrome a Different Entity from Budd-Chiari Syndrome in Children?Waheed N1, Cheema HA1, Suleman H1, Mushtaq I1, Fayyaz Z1, Anjum N1. Abstract OBJECTIVE: To differentiate between clinical and demographic spectrum, and outcome in hepatovenocaval syndrome (HVCS) and Budd-Chiari syndrome (BCS). STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Division of Pediatric Gastroenterology, Hepatology and Nutrition, The ChildrenHospital, Lahore, from January 2014 to January 2017. METHODOLOGY: Published on: Apr-2018 Read more	Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study https://www.ncbi.nlm.nih.gov/pubmed/29519540 J Pediatr. 2018 Mar 5. pii: S0022-3476(17)31743-2. doi: 10.1016/j.jpeds.2017.12.048. [Epub ahead of print] Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study. Ng VL1, Sorensen LG2, Alonso EM3, Fredericks EM4, Ye W5, Moore J5, Karpen SJ6, Shneider BL7, Molleston JP8, Bezerra JA9, Murray KF10, Loomes KM11, Rosenthal P12, Squires RH13, Wang K14, Arnon R15, Schwarz KB16, Turmelle YP17, Haber BH11, Sherker AH18, Magee JC19, Sokol RJ20; Childhood Liver Disease Research Network (ChiLDReN). Abstract OBJECTIVES: Published on: Mar-2018 Read more
Dyslipidemia is associated with pediatric nonalcoholic fatty liver disease https://www.ncbi.nlm.nih.gov/pubmed/29699915 NAFLD J Clin Lipidol. 2018 Apr 3. pii: S1933-2874(18)30194-6. doi: 10.1016/j.jacl.2018.03.089. [Epub ahead of print]Dyslipidemia is associated with pediatric nonalcoholic fatty liver disease. Dowla S1, Aslibekyan S2, Goss A3, Fontaine K4, Ashraf AP5. Abstract BACKGROUND: With the increasing prevalence of childhood obesity, nonalcoholic fatty liver disease (NAFLD) has emerged as the most common cause of pediatric chronic liver disorder. Factors underlying the pathophysiology of NAFLD remain poorly defined. OBJECTIVE: This study aimed to describe the metabolic characteristics of children with NAFLD differing in race/ethnicity and to test associations between dyslipidemia and NAFLD. METHODS: Published on: Apr-2018 Read more	Update on the management of hepatitis B and C infections in the neonatal period https://www.ncbi.nlm.nih.gov/pubmed/29526383 Semin Perinatol. 2018 Mar 8. pii: S0146-0005(18)30012-0. doi: 10.1053/j.semperi.2018.02.006. [Epub ahead of print] Update on the management of hepatitis B and C infections in the neonatal period. Espinosa CM1, Jhaveri R2. Abstract Published on: Mar-2018 Read more
Investigation of Blood Betatrophin Levels in Obese Children with Non-Alcoholic Fatty Liver Disease https://www.ncbi.nlm.nih.gov/pubmed/29713608 NAFLD Pediatr Gastroenterol Hepatol Nutr. 2018 Apr;21(2):111-117. doi: 10.5223/pghn.2018.21.2.111. Epub 2018 Apr 13. Battal F1, Türkön H2, Aylanç N3, Aylanç H1, Yıldırım Ş1, Kaymaz N Abstract PURPOSE: The prevalence of obesity has significantly increased among children and adolescents worldwide and is becoming an important health care problem in parallel with the increased prevalence of obesity pediatric non-alcoholic fatty liver disease. Betatrophin is a newly define hormone that is commonly secreted by liver and plays role in glucose tolerance. This study aimed to investigate the relationship between serum betatrophin levels and non-alcoholic fatty liver disease in obese children. METHODS: Published on: Apr-2018 Read more	Wilson disease and lupus nephritis: is it coincidence or a true association? https://www.ncbi.nlm.nih.gov/pubmed/29528784 Paediatr Int Child Health. 2018 Mar 12:1-4. doi: 10.1080/20469047.2018.1443411. [Epub ahead of print] Wilson disease and lupus nephritis: is it coincidence or a true association? Pradhan S1, Krishnamurthy S1, Jagadisan B1, Rajesh NG2, Kaliaperumal S3, Ramasamy S1, Subramanian N1. Abstract Published on: Mar-2018 Read more
Accuracy of the 2008 Simplified Criteria for the Diagnosis of Autoimmune Hepatitis in Children https://www.ncbi.nlm.nih.gov/pubmed/29713609 Autoimmune hepatitis Pediatr Gastroenterol Hepatol Nutr. 2018 Apr;21(2):118-126. doi: 10.5223/pghn.2018.21.2.118. Epub 2018 Apr 13.Arcos-Machancoses JV1, Molera Busoms C1,2, Julio Tatis E1, Victoria Bovo M1, Quintero Bernabeu J3,2, Juampérez Goñi J3,2, Crujeiras Martínez V4, Martin de Carpi J1,2. Abstract PURPOSE: Classical criteria for diagnosis of autoimmune hepatitis (AIH) are intended as research tool and are difficult to apply at patient's bedside. We aimed to study the accuracy of simplified criteria and the concordance with the expert diagnosis based on the original criteria. METHODS: Published on: Apr-2018 Read more	Systematic Review: the Epidemiology, Natural History and Burden of Alagille Syndrome https://www.ncbi.nlm.nih.gov/pubmed/29543694 J Pediatr Gastroenterol Nutr. 2018 Mar 14. doi: 10.1097/MPG.0000000000001958. [Epub ahead of print]Systematic Review: the Epidemiology, Natural History and Burden of Alagille Syndrome. Kamath BM1, Baker A2, Houwen R3, Todorova L4, Kerkar N5. Abstract BACKGROUND: Alagille syndrome (ALGS) is an inherited multisystem disorder typically manifesting as cholestasis, and potentially leading to end-stage liver disease and death. AIM: To perform the first systematic review of the epidemiology, natural history and burden of ALGS with a focus on the liver component. METHODS: Published on: Mar-2018 Read more
The search for noninvasive methods to identify liver fibrosis in children with nonalcoholic fatty liver disease https://www.ncbi.nlm.nih.gov/pubmed/29517271 Biomark Med. 2018 Mar;12(3):265-273. doi: 10.2217/bmm-2017-0038. Epub 2018 Mar 8. The search for noninvasive methods to identify liver fibrosis in children with nonalcoholic fatty liver disease. Mandelia C1, Kabbany MN1, Conjeevaram Selvakumar PK1, Alkhouri N2. Abstract Published on: Mar-2018 Read more	Health Related Quality of Life and Neurocognitive Outcomes in the First Year after Pediatric Acute Liver Failure https://www.ncbi.nlm.nih.gov/pubmed/29551316 J Pediatr. 2018 Mar 16. pii: S0022-3476(18)30054-4. doi: 10.1016/j.jpeds.2018.01.030. [Epub ahead of print] Health Related Quality of Life and Neurocognitive Outcomes in the First Year after Pediatric Acute Liver Failure. Sorensen LG1, Neighbors K2, Hardison RM3, Loomes KM4, Varni JW5, Ng VL6, Squires RH7, Alonso EM2; Pediatric Acute LiverFailure Study Group. Abstract OBJECTIVE: To determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF). STUDY DESIGN: Published on: Mar-2018 Read more

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