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Clinical Efficacy of Percutaneous Transhepatic Portal Vein Angioplasty for Late-Onset Portal Vein Stenosis in Pediatric Liver Transplant Patients https://www.ncbi.nlm.nih.gov/pubmed/29470353 Liver transplantation Transplantation. 2018 Feb 20. doi: 10.1097/TP.0000000000002138. [Epub ahead of print] Naik KB, Hawkins CM, Gill AE, Gupta NA. Abstract BACKGROUND: Stenosis of the portal vein (PV) is a rare complication after liver transplantation (LT) in pediatric patients and it adversely affects outcomes. We reviewed the safety and efficacy of percutaneous transhepatic balloon angioplasty (PTBA) as a treatment for post-LT late-onset portal vein stenosis (PVS). METHODS: 318 patients between the ages of 0-21 years received a LT from 2001 to 2016 at this tertiary center. 21 children were evaluated for PVS using percutaneous portal venography. RESULTS: Published on: Feb-2018 Read more	Taliglucerase alfa: safety and efficacy across 6 clinical studies in adults and children with Gaucher disease. https://www.ncbi.nlm.nih.gov/pubmed/29471850 Gauchers Orphanet J Rare Dis. 2018 Feb 23;13(1):36. doi: 10.1186/s13023-018-0776-8. Zimran A, Wajnrajch M, Hernandez B, Pastores GM. Abstract Published on: Feb-2018 Read more
Diagnostic Performance of MR Elastography for Liver Fibrosis in Children and Young Adults with a Spectrum of Liver Diseases https://www.ncbi.nlm.nih.gov/pubmed/29470938 Radiology. 2018 Feb 22:172099. doi: 10.1148/radiol.2018172099. [Epub ahead of print]. Trout AT, Sheridan RM, Serai SD, Xanthakos SA, Su W, Zhang B, Wallihan DB. Abstract Published on: Feb-2018 Read more	Maternal viral load and hepatitis B virus mother-to-child transmission risk: a systematic review and meta-analysis https://www.ncbi.nlm.nih.gov/pubmed/29473269 Hepatitis B Hepatol Res. 2018 Feb 23. doi: 10.1111/hepr.13072. [Epub ahead of print] Chen HL, Zha ML, Cai JY, Qin G. Abstract OBJECTIVES: The aim of this study was to assess the relationship between maternal viral load and mother-to-childtransmission (MTCT) risk in HBeAg-positive mothers. METHODS: PubMed and Web of Science were systematically searched. We compared MTCT incidence between maternal hepatitis B virus (HBV) DNA positive and negative group. We also examined the dose-response effect of this relationship. RESULTS: Published on: Feb-2018 Read more
Pediatric Fatty Liver Disease (PeFLD): all is not NAFLD - pathophysiological insights and approach to management https://www.ncbi.nlm.nih.gov/pubmed/29471012 NAFLD J Hepatol. 2018 Feb 19. pii: S0168-8278(18)30123-5. doi: 10.1016/j.jhep.2018.02.006. [Epub ahead of print] .Hegarty R, Deheragoda M, Fitzpatrick E, Dhawan A. Abstract Published on: Feb-2018 Read more	Acute liver failure in children-Is living donor liver transplantation justified? https://www.ncbi.nlm.nih.gov/pubmed/29474400 PLoS One. 2018 Feb 23;13(2):e0193327. doi: 10.1371/journal.pone.0193327. eCollection2018. Szymczak M, Kaliciński P, Kowalewski G, Broniszczak D, Markiewicz-Kijewska M, Ismail H, Stefanowicz M, Kowalski A, Teisseyre J, Jankowska I, Patkowski W. Abstract OBJECTIVES: Living donor liver transplantation (LDLT) in patients with acute liver failure (ALF) has become an acceptable alternative to transplantation from deceased donors (DDLT). The aim of this study was to analyze outcomes of LDLT in pediatric patients with ALF based on our center's experience. MATERIAL AND METHODS: Published on: Feb-2018 Read more
Nonalcoholic Fatty Liver Disease in Children https://www.ncbi.nlm.nih.gov/pubmed/29471561 NAFLD Semin Liver Dis. 2018 Feb;38(1):1-13. doi: 10.1055/s-0038-1627456. Epub 2018 Feb 22.. Mann JP, Valenti L, Scorletti E, Byrne CD, Nobili V. Abstract Published on: Feb-2018 Read more	Reduced Growth Hormone Secretion is Associated with Nonalcoholic Fatty LiverDisease in Obese Children https://www.ncbi.nlm.nih.gov/pubmed/29341046 NAFLD Horm Metab Res. 2018 Jan 16. doi: 10.1055/s-0043-124970. [Epub ahead of print]. Liang S, Yu Z, Song X, Wang Y, Li M, Xue J. Abstract Published on: Jan-2018 Read more
Improvement of life quality measured by Lansky Score after enzymatic replacement therapy in children with Gaucher disease type 1 https://www.ncbi.nlm.nih.gov/pubmed/29471591 Gauchers Mol Genet Genomic Med. 2018 Jan;6(1):27-34. doi: 10.1002/mgg3.339. Epub 2017 Oct 25.. Cerón-Rodríguez M, Barajas-Colón E, Ramírez-Devars L, Gutiérrez-Camacho C, Salgado-Loza JL. Abstract BACKGROUND: Gaucher disease type 1 (GD1, OMIM# 230800), is a condition with high impact in patient's quality of life (QoL). We report the improvement in QoL of children with GD1 measured by Lansky play-performance scale (LS) after enzymatic replacement therapy (ERT) and to describe our experience in the treatment of children with GD1. METHODS: Published on: Feb-2018 Read more	Investigation of Clinical and Pathological Relationships between Adult- and Pediatric-type NASH in Korean Children https://www.ncbi.nlm.nih.gov/pubmed/29349944 NAFLD J Korean Med Sci. 2018 Jan 29;33(5):e34. doi: 10.3346/jkms.2018.33.e34. Yoon J, Park BH, Kim JH, Moon JH, Lee YH, Jang SM, Kim YJ. Abstract BACKGROUND: Histologically, nonalcoholic steatohepatitis (NASH) is categorized into adult-type (type 1) and pediatric-type (type 2). The origination of the histological difference between the two types and how they differ clinically remain uncertain. We aimed to understand the incidence and clinical characteristics of the two types of NASH in Korean children, and to investigate the association between their pathological type and clinical characteristics, using anthropometric and laboratory data. METHODS: Published on: Jan-2018 Read more

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