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Biliary Complications after Hepatic Trauma in Children

https://www.ncbi.nlm.nih.gov/pubmed/29097861

J Emerg Trauma Shock. 2017 Oct-Dec;10(4):211-214. doi: 10.4103/JETS.JETS_136_16.

Biliary Complications after Hepatic Trauma in Children.
Guanà R, Giulia C, Brunati A, Garofalo S, Schleef J.

Abstract

AIM OF THE STUDY:

In pediatric patients with liver trauma and hemodynamic stability, conservative treatment is acknowledged as the gold standard.

PATIENTS AND METHODS:

We conducted a retrospective analysis of 116 consecutive pediatric patients (<14-year-old) observed at our institution for closed abdominal trauma from January 2010 to January 2016. Among these, 16 patients (13%) had hepatic trauma Grade II or more, according to Moore liver trauma injury score.

RESULTS:

Published on: 
Oct-2017
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Quantification of Pediatric Abdominal Organ Motion With a 4-Dimensional Magnetic Resonance Imaging Method.

https://www.ncbi.nlm.nih.gov/pubmed/28816151

Uh J, Krasin MJ, Li Y, Li X, Tinkle C, Lucas JT Jr, Merchant TE, Hua C.

Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):227-237. doi: 10.1016/j.ijrobp.2017.05.026. Epub 2017 May 25.

Abstract

PURPOSE:

To characterize respiration-induced abdominal organ motion in children receiving radiation treatment with a 4-dimensional (4D) magnetic resonance imaging (MRI) method.

METHODS AND MATERIALS:

Published on: 
Sep-2017
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Molecular signature of active fibrogenesis prevails in biliary atresia after successful portoenterostomy.

https://www.ncbi.nlm.nih.gov/pubmed/28655415 Biliary atresia

Kerola A, Lampela H, Lohi J, Heikkilä P, Mutanen A, Jalanko H, Pakarinen MP.

Surgery. 2017 Sep;162(3):548-556. doi: 10.1016/j.surg.2017.04.013. Epub 2017 Jun 24.

Abstract

BACKGROUND:

In biliary atresia mechanisms of progressive liver injury leading to need of liver transplantation after successful portoenterostomy remain unknown. A better understanding is a prerequisite for development of novel therapies to extend native liversurvival, and we aimed to unravel molecular characteristics of liver injury after successful portoenterostomy.

METHODS:

Published on: 
Sep-2017
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Expanding the Margins: High Volume Utilization of Marginal Liver Grafts Among >2000 Liver Transplants at a Single Institution.

https://www.ncbi.nlm.nih.gov/pubmed/28657945 Liver transplant

Halazun KJ1, Quillin RC, Rosenblatt R, Bongu A, Griesemer AD, Kato T, Smith C, Michelassi F, Guarrera JV, Samstein B, Brown RS Jr, Emond JC.

Ann Surg. 2017 Sep;266(3):441-449. doi: 10.1097/SLA.0000000000002383.

Abstract

OBJECTIVE:

Marginal livers (ML) have been used to expand the donor pool. National utilization of MLs is variable, and in some centers, they are never used. We examined the outcomes of MLs in the largest single center series of MLs used to date and compared outcomes to standard (SL) and living donor (LD) livers.

METHODS:

Published on: 
Sep-2017
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Elevated Hemoglobin Level is Associated With Advanced Fibrosis in Pediatric Non Alcoholic Fatty Liver Disease.

https://www.ncbi.nlm.nih.gov/pubmed/28556786 NAFLD

Giorgio V1, Mosca A, Alterio A, Alisi A, Grieco A, Nobili V, Miele L. J Pediatr Gastroenterol Nutr. 2017 Apr 27. doi: 10.1097/MPG.0000000000001614. [Epub ahead of print]

Abstract

OBJECTIVES:
Hemoglobin (Hb) and red blood cell distribution width (RDW) have been reported to be a risk marker of metabolic syndrome (MS) and nonalcoholic fatty liver disease (NAFLD). No study exists on pediatric populations. We aimed to determine the association between hematological parameters, and the severity of disease in children with biopsy proven NAFLD.

METHODS:

Published on: 
Aug-2017
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A 4 and a half years old boy with mesenchymal hamartomas in the left lateral lobe of the liver: A case report and literature review.

https://www.ncbi.nlm.nih.gov/pubmed/28767567

Liao W1, Zhang B, Zhang W, Chen L, Zhang W, Zhang B, Chen X.

Medicine (Baltimore). 2017 Aug;96(31):e7281. doi: 10.1097/MD.0000000000007281.

Abstract

RATIONALE:

Mesenchymal hamartomas of the liver is one type of rare liver tumor.

PATIENT CONCERNS:

Mesenchymal hamartomas of the liver (MHL) is rarely reported in the left lobe of the liver in children who are more than 2 years old. It is difficult to distinguish it from liver lesions such as hepatoblastoma in children, and hepatocellular carcinoma and focal nodular hyperplasia in adults. In addition, it is hard to correctly diagnose it without pathological examination.

DIAGNOSES:

Mesenchymal hamartomas of the liver.

INTERVENTIONS:

Published on: 
Sep-2017
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Systematic Review: Nutrition and Physical Activity in the Management of Paediatric Nonalcoholic Fatty Liver Disease

https://www.ncbi.nlm.nih.gov/pubmed/28737568
.
Gibson PS1, Lang S, Dhawan A, Fitzpatrick E, Blumfield ML, Truby H, Hart KH, Moore JB. J Pediatr Gastroenterol Nutr. 2017 Aug;65(2):141-149. doi: 10.1097/MPG.0000000000001624.

Abstract

OBJECTIVES:
The aim of the study was to evaluate efficacy of nutrition and physical activity interventions in the clinical management of paediatric nonalcoholic fatty liver disease. The prevalence of paediatric nonalcoholic fatty liver disease continues to rise alongside childhood obesity. Weight loss through lifestyle modification is currently first-line treatment, although supplementation of specific dietary components may be beneficial.

METHODS:

Published on: 
Aug-2017
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