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Noninvasive assessment of liver steatosis in children: the clinical value of controlled attenuation parameter https://www.ncbi.nlm.nih.gov/pubmed/28472948 Ferraioli G, Calcaterra V, Lissandrin R, Guazzotti M, Maiocchi L, Tinelli C, De Silvestri A, Regalbuto C, Pelizzo G, Larizza D, Filice C. BMC Gastroenterol. 2017 May 4;17(1):61. doi: 10.1186/s12876-017-0617-6. Abstract BACKGROUND: To assess the clinical validity of controlled attenuation parameter (CAP) in the diagnosis of hepatic steatosis in a series of overweight or obese children by using the imperfect gold standard methodology. METHODS: Published on: May-2017 Read more	King's Variceal Prediction Score: A Novel Noninvasive Marker of Portal Hypertension in Pediatric Chronic Liver Disease https://www.ncbi.nlm.nih.gov/pubmed/27749613 Witters P, Hughes D, Karthikeyan P, Ramakrishna S, Davenport M, Dhawan A, Grammatikopoulos T. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):518-523. doi: 10.1097/MPG.0000000000001423. Abstract BACKGROUND AND AIMS: Variceal haemorrhage can be a life-threatening complication of chronic liver disease in children. There is limited evidence about the optimal prophylactic management and selection criteria of children who will benefit from upper gastrointestinal endoscopy. METHODS: Published on: Apr-2017 Read more
Magnetic Resonance Elastography Measured Shear Stiffness as a Biomarker of Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease https://www.ncbi.nlm.nih.gov/pubmed/28493388 Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. Hepatology. 2017 May 11. doi: 10.1002/hep.29241 Abstract Published on: May-2017 Read more	Correlation of Transient Elastography With Severity of Cystic Fibrosis-related Liver Disease https://www.ncbi.nlm.nih.gov/pubmed/27782957 Aqul A, Jonas MM, Harney S, Raza R, Sawicki GS, Mitchell PD, Fawaz R. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):505-511. doi: 10.1097/MPG.0000000000001448. Abstract OBJECTIVES: The aim of the study was to evaluate whether liver stiffness measurement (LSM), determined by transient elastography, correlates with presence and severity of liver disease in children and young adults with cystic fibrosis (CF). METHODS: Published on: Apr-2017 Read more
Hepaticon 2017 Videos Read more	Survey on Clinical Practice of Primary Prophylaxis in Portal Hypertension in Children https://www.ncbi.nlm.nih.gov/pubmed/27801752 Jeanniard-Malet O, Duché M, Fabre A. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):524-527. doi: 10.1097/MPG.0000000000001453. Abstract Published on: Apr-2017 Read more
Hepatic Inflammation May Influence Liver Stiffness Measurements by Transient Elastography in Children and Young Adults. https://www.ncbi.nlm.nih.gov/pubmed/27540711 Raizner A, Shillingford N, Mitchell PD, Harney S, Raza R, Serino J, Jonas MM, Lee CK. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):512-517. doi: 10.1097/MPG.0000000000001376. Abstract OBJECTIVES: Transient elastography (TE) measures liver stiffness to assess fibrosis. Studies in adults have shown that inflammation increases stiffness, leading to an overestimation of fibrosis. We investigated the contribution of inflammation to liver stiffness measurements (LSMs) in children/young adults. METHODS: Published on: Apr-2017 Read more	Hepatic Issues and Complications Associated With Inflammatory Bowel Disease: A Clinical Report https://www.ncbi.nlm.nih.gov/pubmed/27984347 Hepatic Issues and Complications Associated With Inflammatory Bowel Disease: A Clinical Report From the NASPGHAN Inflammatory Bowel Disease and Hepatology Committees. Saubermann LJ, Deneau M, Falcone RA, Murray KF, Ali S, Kohli R, Ekong UD, Valentino PL, Grossman AB, Rand EB, Jonas MM, Saeed SA, Kamath BM. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):639-652. doi: 10.1097/MPG.0000000000001492. Abstract Published on: Apr-2017 Read more
Family Impact and Infant Emotional Outcomes Following Diagnosis of Serious Liver Disease or Transplantation in Infancy https://www.ncbi.nlm.nih.gov/pubmed/27673709 Bowden MR, Ee LC, Krishnan U, O'Loughlin EV, Hardikar W, Carmody D, Hainsworth C, Jermyn V, Lee MM, Sawyer J, Stormon M, Holmes K, Lemberg DA, Day AS, Paul C, Hazell P. J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):528-532. doi: 10.1097/MPG.0000000000001404. Abstract OBJECTIVES: Research is lacking into the emotional effects on families of serious chronic illness in infants. We examined the effect of the diagnosis of serious liver disease in infants upon parent psychological symptoms and family functioning. We hypothesized that parent psychological symptoms, family functioning, and father engagement will predict infant emotional outcomes. METHODS: Published on: Apr-2017 Read more	Minimal hepatic encephalopathy in children with chronic liver disease: Prevalence, pathogenesis and magnetic resonance-based diagnosis. https://www.ncbi.nlm.nih.gov/pubmed/27815224 Hepatic Encephalopathy Srivastava A, Chaturvedi S, Gupta RK, Malik R, Mathias A, Jagannathan NR, Jain S, Pandey CM, Yachha SK, Rathore RK. J Hepatol. 2017 Mar;66(3):528-536. Abstract BACKGROUND & AIMS: Data on minimal hepatic encephalopathy (MHE) in children is scarce. We aimed to study MHE in children with chronic liver disease (CLD) and to validate non-invasive objective tests which can assist in its diagnosis. METHODS: Published on: Mar-2017 Read more

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