Event Videos

A multidisciplinary approach to laparoscopic sleeve gastrectomy among multiethnic adolescents in the United States.

https://www.ncbi.nlm.nih.gov/pubmed/28697852

Jaramillo JD1, Snyder E1, Farrales S2, Stevens M2, Wall JK2, Chao S2, Morton J1, Pratt JS2, Hammer L3, Shepard WE3, Bruzoni M4.

ABSTRACT

BACKGROUND:
Childhood obesity has become a serious public health problem in our country with a prevalence that is disproportionately higher among minority groups. Laparoscopic sleeve gastrectomy (LSG) is gaining attention as a safe bariatric alternative for severely obese adolescents.

STUDY DESIGN:
A retrospective study on morbidly obese adolescents that underwent LSG at our institution from 2009 to 2017. Primary outcomes were weight loss as measured by change in BMI and percent excess weight loss (%EWL) at 1 year after surgery, resolution of comorbidities and occurrence of complications.

Published on: 
Jun-2017
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Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy.

https://www.ncbi.nlm.nih.gov/pubmed/28700730

Diestelhorst J1,2, Junge N2, Schlue J3, Falk CS4, Manns MP1, Baumann U2, Jaeckel E1, Taubert R1.

ABSTRACT

BACKGROUND & AIMS:
The autoimmune hepatitis (AIH) is a chronic hepatitis driven by the adaptive immunity that affects all age groups. A functional and numerical regulatory T cell (Treg) defect has been reported in pediatric AIH (pAIH), while an intrahepatic increase in adult AIH (aAIH) patients has been detected in current research findings.

METHODS:
Therefore, we quantified the intrahepatic numbers of Treg, T and B cells, as well as serum cytokine levels before and during therapy in pAIH.

RESULTS:

Published on: 
Jun-2017
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Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis.

https://www.ncbi.nlm.nih.gov/pubmed/28027587

Wang KS, Tiao G, Bass LM, Hertel PM, Mogul D, Kerkar N, Clifton M, Azen C, Bull L, Rosenthal P, Stewart D, Superina R, Arnon R, Bozic M, Brandt ML, Dillon PA, Fecteau A, Iyer K, Kamath B, Karpen S, Karrer F, Loomes KM, Mack C, Mattei P, Miethke A, Soltys K, Turmelle YP, West K, Zagory J, Goodhue C, Shneider BL; Childhood Liver Disease Research Network (ChiLDReN).Hepatology. 2017 May;65(5):1645-1654. doi: 10.1002/hep.29019. Epub 2017 Mar 22.

Abstract

Published on: 
May-2017
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Low Birthweight Increases the Likelihood of Severe Steatosis in Pediatric Non-Alcoholic Fatty Liver Disease

https://www.ncbi.nlm.nih.gov/pubmed/28555633

Elisabetta Bugianesi, Carla Bizzarri, Chiara Rosso, Antonella Mosca, Nadia Panera, Silvio Veraldi, Andrea Dotta, Germana Giannone, Massimiliano Raponi, Marco Cappa, Anna Alisi and Valerio Nobili

ABSTRACT

Objectives:
Small for gestational age (SGA) is associated with an increased risk of non-alcoholic fatty liver disease (NAFLD). Our aim was to investigate the correlation of birthweight with the severity of liver damage in a large cohort of children with NAFLD.

Methods:

Published on: 
Jun-2017
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Presenting Features and Prognosis of Ischemic and Nonischemic Neonatal Liver Failure.

https://www.ncbi.nlm.nih.gov/pubmed/28437325

Zozaya Nieto C, Fernández Caamaño B, Muñoz Bartolo G, Menéndez Suso JJ, Frauca Remacha E, Valverde Núñez E.J Pediatr Gastroenterol Nutr. 2017 May;64(5):754-759. doi: 10.1097/MPG.0000000000001501.

Abstract

OBJECTIVES:
To describe the epidemiological features, clinical characteristics and outcomes of neonates diagnosed with liver failure, as well as determine prognostic factors.

METHODS:

Published on: 
May-2017
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Scrub typhus causing neonatal hepatitis with acute liver failure—A case series

https://www.ncbi.nlm.nih.gov/pubmed/28612320

Shailja Vajpayee, R K Gupta, M L Gupta

Abstract

Neonatal hepatitis with acute liver failure due to varied etiology including various infections is reported in the past. Scrub typhus as a cause of neonatal hepatitis has rarely been reported in literature. A high index of clinical suspicion is required for early diagnosis and timely treatment. Severity and prognosis of the disease varies widely because several different strains of Orientia tsutsugamushi exist with different virulence. Delayed diagnosis can result in complication and significant morbidity and mortality. Here, we report three cases of neonatal hepatitis with acute liver failure caused by scrub typhus to increase awareness.

KEYWORDS:

Published on: 
Jun-2017
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Noncirrhotic Portal Fibrosis in Pediatric Population

https://www.ncbi.nlm.nih.gov/pubmed/28437324

Sood V, Lal BB, Khanna R, Rawat D, Bihari C, Alam S. J Pediatr Gastroenterol Nutr. 2017 May;64(5):748-753. doi: 10.1097/MPG.0000000000001485

Abstract

OBJECTIVES:
Noncirrhotic portal fibrosis (NCPF) has been classically described as a disease of young to middle age with limited literature regarding its occurrence, onset, or clinical presentation in children. We hereby present a series of 19 patients diagnosed and managed as NCPF in pediatric age group.

METHODS:
A retrospective review of all the patients presenting to the pediatric hepatology department (age <18 years) and diagnosed as NCPF was done and data were evaluated.

RESULTS:

Published on: 
May-2017
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Favorable Outcomes of Preterm Infants With Parenteral Nutrition-associated Liver Disease Treated With Intravenous Fish Oil-based Lipid Emulsion.

https://www.ncbi.nlm.nih.gov/pubmed/28437326

Sorrell M, Moreira A, Green K, Jacob R, Tragus R, Keller L, Quinn A, McCurnin D, Gong A, El Sakka A, Mittal N, Blanco C. J Pediatr Gastroenterol Nutr. 2017 May;64(5):783-788. doi: 10.1097/MPG.0000000000001397

Abstract

OBJECTIVES:
The aim of the study was to determine the acute and long-term outcomes of preterm infants treated with an intravenous fish oil-based lipid emulsion (FishLE) for parenteral nutrition-associated liver disease (PNALD).

METHODS:

Published on: 
May-2017
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