Autoimmune Hepatitis

Diarrhea and Hepatosplenomegaly

Source Event :Case discussions in Pediatric Liver Diseases organised by Children's Liver Foundation and Indian Academy of pediatric, Mumbai on 14th and 15th December 2013.
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Presented by
Dr Ravindra Kumar Sharma
Moderated by
Dr Vishnu Biradar
Panelists
Dr Malathi Sathiyasekaran
Dr Girish Gupte
Dr Rajesh Sainani

GOOD CORRELATION BETWEEN LIVER STIFFNESS MEASUREMENT AND APRI, FIB-4, PLATELET COUNT, IN PEDIATRIC AUTOIMMUNE HEPATITIS

Leptin gene Polymorphism and Leptin protein levels in Pediatric Autoimmune Hepatitis

The etiology and differential diagnosis of "autoimmune hepatitis-like liver disease" in children: a single-center retrospective study

Epidemiology, clinical features and management of autoimmune hepatitis in Switzerland: a retrospective and prospective cohort study

Long-term outcomes of patients with type 1 or 2 autoimmune hepatitis presenting in childhood

Autoimmune Antibodies in Children and Adolescents with Nonalcoholic Fatty Liver Disease

Kupffer Cell Hyaline Globules in Children With Autoimmune Hepatitis

Seronegative autoimmune hepatitis in children : A real diagnostic challenge

Autoimmune Hepatitis: Predictors of Native Liver Survival in Children and Adolescents

Multiparametric MRI as a Non-Invasive Monitoring Tool for Children with Autoimmune Hepatitis

Evaluation of frequency of autoimmune hepatitis autoantibodies in children with type 1 diabetes

Characteristics and Outcomes of Autoimmune Hepatitis from a Tertiary Paediatric Centre, Cape Town, South Africa.

Seamless Management of Juvenile Autoimmune Liver Disease: Long-Term Medical and Social Outcome.

Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis.

Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the study of liver diseases.

Acute onset of autoimmune hepatitis in children and adolescents

Development and validation of a new simplified diagnostic scoring system for pediatric autoimmune hepatitis.

Steroid Free Treatment of Autoimmune Hepatitis in Selected Children

Racial Disparities in Presentation and Outcomes of Pediatric Autoimmune Hepatitis.

Adequacy of scoring systems in diagnosing paediatric autoimmune hepatitis: retrospective study using a control group children with Hepatitis B infection

An 8-Year-Old Girl with Autoimmune Hepatitis Following Aplastic Anemia.

Pediatric autoimmune liver disease and extra-hepatic immune-mediated comorbidities

Old and New Treatments for Pediatric Autoimmune Hepatitis

Autoimmune hepatitis in 828 Brazilian children and adolescents: clinical and laboratory findings, histological profile, treatments, and outcomes

Accuracy of the 2008 Simplified Criteria for the Diagnosis of Autoimmune Hepatitis in Children

Evolving Practice and Changing Phenotype in Pediatric Autoimmune LiverDisease: Outcomes From an Australian Center

Autoimmune Hepatitis in Children and Adolescents: Effect on Quality of Life

New Onset Autoimmune Hepatitis during Anti-Tumor Necrosis Factor-Alpha Treatment in Children.

Histological improvement of liver fibrosis in well-treated patients with autoimmune hepatitis: A cohort study.

Histological Changes in Autoimmune Hepatitis with Graves' Disease: A Child Case Report.

Outcomes in Pediatric Autoimmune Hepatitis and Significance of Azathioprine Metabolites

Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy.

Outcomes in Pediatric Autoimmune Hepatitis and Significance of Azathioprine Metabolites.

Validation of transient elastography in autoimmune hepatitis: timing determines the impact of inflammation and fibrosis

Autoimmune hepatitis and long-term disease course in children in Turkey, a single-center experience.

Centrilobular zonal necrosis as a hallmark of a distinctive subtype of autoimmune hepatitis. Aizawa Y, Abe H, Sugita T, S

EASL Clinical Practice Guidelines: Autoimmune hepatitis

Prediction of short- and long-term outcome in patients with autoimmune hepatitis

Fulminant presentation of autoimmune hepatitis: clinical features and early predictors of corticosteroid treatment failure

Fulminant hepatic failure of autoimmune aetiology in children

Seroprevalence of celiac disease in patients with autoimmune hepatitis

Noninvasive markers in the assessment and management of autoimmune liver diseases

Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome

Outcome after discontinuation of immunosuppression in children with autoimmune hepatitis: a population-based study

Autoantibody and human leukocyte antigen profiles in children with autoimmune liver disease and their first-degree relatives

Antismooth muscle and antiactin antibodies are indirect markers of histological and biochemical activity of autoimmune hepatitis

Health-related quality of life in children with autoimmune liver disease.

Celiac Disease–Associated Autoimmune Hepatitis in Childhood: Long-Term Response to Treatment

Autoimmune Hepatitis in Children in Eastern Denmark.

AUTOIMMUNE HEPATITIS

What is autoimmune hepatitis?

‘Autoimmune’ is made of two words- ‘auto’ +’immune’- implying altered immunity to cells of one’s own body. Immune system normally recognises ‘self ‘and ‘non-self’ cells. It kills only the ‘non-self’ cells. When there is an alteration in the immune system, it loses this ability to differentiate ‘self’ from ‘non self’; and kills ‘self’ cells.

When such attack of the immune system involves cells of liver, it causes Autoimmune Hepatitis. It may occur as only hepatitis or may occur as a part of other autoimmune diseases.

 

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