Success Stories

Event Videos

Congenital Vascular Malformations of the Liver: An Association With Trisomy 21 https://www.ncbi.nlm.nih.gov/pubmed/27602703 Burdall OC, Grammatikopoulos T, Sellars M, Hadzic N, Davenport M. J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):e141-e146. Abstract Published on: Nov-2016 Read more	Non-cirrhotic Portal Fibrosis in Pediatric Population https://www.ncbi.nlm.nih.gov/pubmed/27906797 Sood V, Lal BB, Khanna R, Rawat D, Sharma CB, Alam S. J Pediatr Gastroenterol Nutr. 2016 Nov 30. Abstract BACKGROUND: Non-cirrhotic portal fibrosis (NCPF) has been classically described as a disease of young to middle age with limited literature regarding its occurrence, onset or clinical presentation in children. We hereby present a series of 19 patients diagnosed and managed as NCPF in pediatric age group. METHODS: A retrospective review of all the patients presenting to the pediatric hepatology department (age < 18 years) and diagnosed as NCPF was done and data was evaluated. RESULTS: Published on: Nov-2016 Read more
Complications of Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients; A Systematic Literature Review and Meta-Analysis https://www.ncbi.nlm.nih.gov/pubmed/27663215 Usatin D, Fernandes M, Allen IE, Perito ER, Ostroff J, Heyman MB. J Pediatr. 2016 Dec;179:160-165.e3. doi: 10.1016/j.jpeds.2016.08.046. Abstract OBJECTIVES: To systematically review risks and summarize reported complication rates associated with the performance of endoscopic retrograde cholangiopancreatography (ERCP) in children during the past 2 decades. STUDY DESIGN: Published on: Nov-2016 Read more	NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children https://www.ncbi.nlm.nih.gov/pubmed/27906803 Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. J Pediatr Gastroenterol Nutr. 2016 Nov 30. Abstract Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease that occurs in the setting of insulin resistance and increased adiposity. It has rapidly evolved into the most common liver disease seen in the pediatric population and is a management challenge for general pediatric practitioners, subspecialists and for health systems. In this guideline, the expert committee on NAFLD (ECON) reviewed and summarized the available literature, formulating recommendations to guide screening and clinical care of children with NAFLD. Published on: Nov-2016
Space Occupying Lesions in the Liver https://www.ncbi.nlm.nih.gov/pubmed/27783314 Thyagarajan MS, Sharif K. Indian J Pediatr. 2016 Nov;83(11):1291-1302 Abstract Published on: Nov-2016 Read more	Long-Term Ursodeoxycholic Acid Therapy Does Not Alter Lithocholic Acid Levels in Patients with Cystic Fibrosis with Associated Liver Disease https://www.ncbi.nlm.nih.gov/pubmed/27297203 . Colombo C, Crosignani A, Alicandro G, Zhang W, Biffi A, Motta V, Corti F, Setchell KD. J Pediatr. 2016 Oct;177:59-65.e1. doi: 10.1016/j.jpeds.2016.05.008. Abstract OBJECTIVE: To evaluate the fasting and postprandial serum bile acid composition in patients with cystic fibrosis-associated liver disease (CFLD) after chronic administration of ursodeoxycholic acid (UDCA) (20 mg/kg/day). The aim was to specifically focus on the extent of biotransformation of UDCA to its hepatotoxic metabolite, lithocholic acid, because of recent concerns regarding the safety of long-term, high-dose UDCA treatment for CFLD. STUDY DESIGN: Published on: Oct-2016 Read more
Serum Acetaminophen Protein Adduct Concentrations in Pediatric Emergency Department Patients https://www.ncbi.nlm.nih.gov/pubmed/27846064 Heard K, Anderson V, Dart RC, Kile D, Lavonas E, Green JL. J Pediatr Gastroenterol Nutr. 2016 Nov 14. Abstract Acetaminophen toxicity is a common cause of pediatric liver failure. The diagnosis may be limited by the short window of detection of acetaminophen in serum. Recently acetaminophen protein adducts (APAP-CYS) have been used as a biomarker with a longer duration of detection. The objective of this study was to describe the serum concentrations of APAP-CYS in pediatric patients with and without reported therapeutic acetaminophen exposure. METHODS: Published on: Nov-2016 Read more	King's variceal Prediction Score: A Novel Non-Invasive Marker of Portal Hypertension in Paediatric Chronic Liver Disease https://www.ncbi.nlm.nih.gov/pubmed/27749613 Witters P, Hughes D, Karthikeyan P, Ramakrishna S, Davenport M, Dhawan A, Grammatikopoulos T. J Pediatr Gastroenterol Nutr. 2016 Oct 4. Abstract BACKGROUND AND AIMS: Variceal haemorrhage can be a life-threatening complication of chronic liver disease in children. There is limited evidence about the optimal prophylactic management and selection criteria of children who will benefit from upper gastrointestinal endoscopy. METHODS: Published on: Oct-2016 Read more
Non-cirrhotic Portal Fibrosis in Pediatric Population https://www.ncbi.nlm.nih.gov/pubmed/27906797 Sood V, Lal BB, Khanna R, Rawat D, Sharma CB, Alam S. J Pediatr Gastroenterol Nutr. 2016 Nov 30. Abstract BACKGROUND: Non-cirrhotic portal fibrosis (NCPF) has been classically described as a disease of young to middle age with limited literature regarding its occurrence, onset or clinical presentation in children. We hereby present a series of 19 patients diagnosed and managed as NCPF in pediatric age group. METHODS: A retrospective review of all the patients presenting to the pediatric hepatology department (age < 18 years) and diagnosed as NCPF was done and data was evaluated. RESULTS: Published on: Nov-2016 Read more	Liver Transplantation for Children with Primary Sclerosing Cholangitis and Autoimmune Hepatitis: UNOS Database Analysis. https://www.ncbi.nlm.nih.gov/pubmed/27755342 Jossen J, Annunziato R, Kim HS, Chu J, Arnon R. J Pediatr Gastroenterol Nutr. 2016 Oct 13. Abstract OBJECTIVES: Autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC) are progressive immune-mediated inflammatory diseases that may require liver transplant (LT). Outcomes in children undergoing LT for these diseases are poorly studied in the Pediatric End Stage Liver Disease (PELD) era. We aimed to characterize the outcome of LT in children with AIH and PSC. METHODS: Children ≤18 years with PSC or AIH who had a first, isolated LT from 2002-2012 were identified from the UNOS database. Graft and patient outcomes were studied. RESULTS: Published on: Oct-2016 Read more

CLF Intro movie

SMS requests to

9224791366

Ask The Expert

Pediatric Liver Specialists in India

Centres offering Genetic Testing for Pediatric Liver Diseases

Financial Aid Offered by Trusts

Follow us on:

Facebook Twitter YouTube